Protein Alignment ADCK5 and adck5

DIOPT Version :10

• Sequence 1: XP_011515209.1
• Gene: ADCK5 / 203054
• HGNCID: 21738
• Length: 654
• Species: Homo sapiens
• Sequence 2: XP_031760516.1
• Gene: adck5 / 100127866
• XenbaseID: XB-GENE-6454664
• Length: 582
• Species: Xenopus tropicalis
• Alignment Length: 590
• Identity: 358/590 - (60%)
• Similarity: 439/590 - (74%)
• Gaps: 28/590 - (4%)

Human    79 VQLCHFHSALLHSRQKPWPSPAVFFRRNVRGLPPR-FSSPT---------PLWRKVLSTAVVG-- 131
            |.||.:|.:.| ||.:..       .:.:.|||.| |.|.|         |..|::|...::|
 Frog     7 VLLCRYHISQL-SRCRTG-------EKILMGLPLRGFCSRTQGVEGLERRPPPRRMLRRLIIGSA 63

Human   132 --APLLLGARYVMAEAREKRRMRLVVDGMGRFGRSLKVGLQISLDYWWCTNVVLRGVEENSPGYL 194
              ||.|....|..:|.:|:||||:::.|:|||.|||.:|.|||:||||.::|.|||.:||||.|.
 Frog    64 LAAPPLGTLLYYGSEPQERRRMRILLQGIGRFWRSLMIGSQISVDYWWTSHVTLRGEDENSPRYE 128

Human   195 EVMSACHQRAADALVAGAISNGGLYVKLGQGLCSFNHLLPPEYTRTLRVLEDRALKRGFQEVDEL 259
            ..||.|||||||.||.||:.|||||||||||||:||||||||||:||||||||||.|...||:||
 Frog   129 AAMSRCHQRAADQLVEGAVQNGGLYVKLGQGLCAFNHLLPPEYTKTLRVLEDRALPRRPNEVNEL 193

Human   260 FLEDFQALPHELFQEFDYQPIAAASLAQVHRAKLHDGTSVAVKVQYIDLRDRFDGDIHTLELLLR 324
            |||||.|....||..||.:|||||||||||||.||:||.|||||||||||||||||:.|||||||
 Frog   194 FLEDFGAPAEHLFLHFDQKPIAAASLAQVHRATLHNGTDVAVKVQYIDLRDRFDGDLKTLELLLR 258

Human   325 LVEVMHPSFGFSWVLQDLKGTLAQELDFENEGRNAERCARELAHFPYVVVPRVHWDKSSKRVLTA 389
            |:|.|||:|||||||:||||||:|||||||||||:|||||:|...|||.|||||||::|||||||
 Frog   259 LIEFMHPTFGFSWVLKDLKGTLSQELDFENEGRNSERCARDLQSLPYVTVPRVHWDRTSKRVLTA 323

Human   390 DFCAGCKVNDVEAIRSQGLAVHDIAEKLIKAFAEQIFYTGFIHSDPHPGNVLVRKGPDGKAELVL 454
            |:|.||||:.||.|:.|||.|.|.|||||:.||||||||||||:|||||||||.|||||||:|||
 Frog   324 DYCEGCKVSSVEGIKEQGLDVRDAAEKLIQVFAEQIFYTGFIHADPHPGNVLVTKGPDGKAQLVL 388

Human   455 LDHGLYQFLEEKDRAALCQLWRAIILRDDAAMRAHAAALGVQDYLLFAEMLMQRPVRLGQLWGSH 519
            ||||||::|.::||.:||:|||:|:||:...|..|:|.|||:||.||.|:|:|||:.:....||
 Frog   389 LDHGLYEYLSKRDRTSLCKLWRSIVLRNRQDMEKHSAELGVKDYFLFCEILLQRPLSVPGAMGS- 452

Human   520 LLSREEAAYMVDMARERFEAVMAVLRELPRPMLLVLRNINTVRAINVALGAPVDRYFLMAKRAVR 584
            .|:|||..||.|||||.|:.:|.|||.||||||||.||:||||.::|:||||.||:.|||:.||:
 Frog   453 ALTREETRYMQDMAREHFDDIMRVLRALPRPMLLVFRNLNTVRCLHVSLGAPADRHILMARSAVK 517

Human   585 GWSRLAGATYRGVYGTSLLRHAKVVWEMLKFEVALRLETLAMRLTALLARALVHLSLVPPAEELY 649
            ||.||||....||     .|...|.||..|||:|||.::|.:|:|:.|.|.|:...::...|::.
 Frog   518 GWRRLAGQNSLGV-----TRWISVTWESFKFELALRWDSLVLRVTSSLLRLLIRFQVIEHNEQME 577

Human   650 QYLET 654
            .:|::
 Frog   578 TFLQS 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ADCK5	XP_011515209.1	ADCK1-like	243..483	CDD:270871	182/239 (76%)
adck5	XP_031760516.1	ADCK1-like	177..428	CDD:270871	185/250 (74%)