Protein Alignment ENPEP and CG9806

DIOPT Version :10

• Sequence 1: NP_001968.3
• Gene: ENPEP / 2028
• HGNCID: 3355
• Length: 957
• Species: Homo sapiens
• Sequence 2: NP_572643.1
• Gene: CG9806 / 31994
• FlyBaseID: FBgn0030222
• Length: 911
• Species: Drosophila melanogaster
• Alignment Length: 925
• Identity: 235/925 - (25%)
• Similarity: 402/925 - (43%)
• Gaps: 131/925 - (14%)

Human    97 VNPVHYDL----HVKPLLEEDTYTGTVSISINLSAPTRYLWLHLRETRITRLPE----------- 146
            :.|:||:|    .|:||.....::|.|.|.:.       :|   ||||...|..
  Fly    27 LRPLHYNLSLLTEVEPLKLSGNFSGEVIIRLR-------VW---RETRTIILSNNGLQVGENVLL 81

Human   147 LKRPSGDQVQVRRCFEYKK--QEYVVVEA-----EEELTPSSGDGLYLLTMEFAGWL---NGSLV 201
            ::|.:|.:|.||:.::...  |..:|..:     ||          |.|.::|:|.|   :|..|
  Fly    82 VRRNTGGRVTVRKMWQASSVHQLGIVFNSMLWLGEE----------YTLVVQFSGQLSRASGYFV 136

Human   202 GFYRTTYTENGQVKSIVATDHEPTDARKSFPCFDEPNKKATYTISITHPKEYGALSNMPVAK--- 263
            |.|..:   ....:.|..|...|..|...||||:.....|.:.:::.||:...|:|||.|.|
  Fly   137 GGYMDS---KHHPQWIAVTQLAPNLANTVFPCFENRTFLAPFILNLAHPRGTNAVSNMRVLKTSD 198

Human   264 EESVDDKWTRTTFEKSVPMSTYLVCFAVHQFDSVKRIS---NSGKPLTIYVQPEQKHTAEYAANI 325
            .|..|..|  |||:::..||...:.|::::|  ..|.|   ..|..||.:::|:.....:||.:|
  Fly   199 HEKDDYVW--TTFQQTPAMSVQKLAFSINRF--TNRTSAEIPKGPALTTWLRPKIADQGDYAISI 259

Human   326 TKSVFDYFEEYFAMNYSLPKLDKIAIPDFGTGAMENWGLITYRETNLLYDPKESASSNQQRVATV 390
            |..:..:|...|...|...|:|::.:||....:.|:.||::|.|...||..:.|.:..:|:||:.
  Fly   260 TPQIIVFFISLFGKPYPAMKIDQLVLPDTAYQSHEHLGLVSYPEAAFLYSAQRSTTRAKQQVASH 324

Human   391 VAHELVHQWFGNIVTMDWWEDLWLNEGFASFFEFLGVNHAETDWQMRDQMLLEDVLPVQEDDSLM 455
            ||.|..|.|..::.....:   ||:.|.:.:.....|::.|..|:..:..::...|.|..:||..
  Fly   325 VAQEFAHHWLSDLENAALY---WLHNGLSDYVSGFAVDNVEPAWRFHELSMVRQALAVLVEDSKS 386

Human   456 SSHPIIVTVTTPDEITSVFDGISYSKGSSILRMLEDWIKPENFQKGCQMYLEK-YQFKNAKTSDF 519
            |::|:.:...:....|.     :..|.:.:.|||...|..:.|....::||:: ::..::..:..
  Fly   387 SAYPMSLAYASKSSDTQ-----ANQKSALLFRMLHSLIGTQAFLNALRLYLQRSHKGSSSNQAFL 446

Human   520 WAALEEAS--------RLPVKEVMDTWTRQMGYPVLNVNGVKN-------ITQKRFLLDPRANPS 569
            |..|:|.|        .:.|.::||:||.|.|||::.|  |:|       :||:|||    .||.
  Fly   447 WHTLQEESDNQMSLRQDIKVSQLMDSWTMQPGYPLIRV--VRNYDTNEVTVTQERFL----RNPG 505

Human   570 QPPSDLGYTWNIPVKWTEDNITSSVLFNRSEKEGITLNSSNPSGNAFLK--INPDHIGFY----- 627
            :........|.:|:.:....|.|.|  :....|.:|......:....|.  ..||....:
  Fly   506 KLMQKRQQCWWVPLTFATAGIDSFV--STLPSEWLTCQGRQTASPLILNEVAQPDKWVVFNLRLA 568

Human   628 ---RVNYEVATWDSIATALS-LNHKTFSSADRASLIDDAFALARAQLLDYKVALNLTKYLKREEN 688
               |:.|:...|..|..||| .|..:.....||.||.|...||.|.::.|.:|||...:|:.|:.
  Fly   569 TPCRITYDERNWQLIGNALSGTNASSIDRFTRAQLISDVLNLAGAGVVTYDLALNFLGHLRNEDE 633

Human   689 FLPWQRVISAVTY------------IISMFEDDKE--LYPMIEEYFQGQVKPIADSLGWNDAGDH 739
            |:.||   :|.||            |||.|:....  |....:|.|:      .|.....:|  :
  Fly   634 FIVWQ---AADTYLEWLHRTLRQTTIISTFKGFMRDLLQTKFDELFK------RDGSAAENA--N 687

Human   740 VTKLLRSSVLGFACKMGDREALNNASSLFEQWLNGTVSLPVNLRLLVYRYGMQNSGNEISWNYTL 804
            :|:|: ..||..:|:.......:.|...|......|..:||:|...:|...:| .|.|..|....
  Fly   688 ITELM-VIVLQLSCRTDLESCADFALKEFAGLTLETNRIPVDLSETIYCTAIQ-FGTEADWTLLR 750

Human   805 EQYQKTSLAQEKEKLLYGLASVKNVTLLSRYLDLLKDTNLIKTQDVFTVIRYISYNSYGKNMAWN 869
            ..|.::::::|:..||..:|..:....|.:.|:|......:...||..:...::.|..|.|:|..
  Fly   751 RLYTRSNVSEERRILLSAMACSRENWALDKLLNLAFAGRYMPKDDVLLIFSAVAQNPLGYNIAKK 815

Human   870 WIQLNWDYLVNRYTLNNRNLGRIVTI-AEPFNTELQLWQMESFFAKYPQAGAG-EKPREQVLETV 932
            ::..|...::..|..|...|.::||: .:...||.:|..:..|.....|...| |....::||..
  Fly   816 YLVDNIKAIIKLYGSNTDELAQLVTVLMKEVTTEEELNALRMFMRTDLQNLPGFEIAFRRILELG 880

Human   933 KNNIEW-LKQHRNTI 946
            ::||.| .:|:.|.:
  Fly   881 EDNISWHNRQYHNLL 895

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ENPEP	NP_001968.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	44..83
		M1_APN-Q_like	100..540	CDD:341064	122/479 (25%)
		ERAP1_C	616..934	CDD:463368	85/344 (25%)
CG9806	NP_572643.1	M1_APN-Q_like	30..474	CDD:341064	121/478 (25%)
		ERAP1_C	560..878	CDD:463368	80/330 (24%)