Protein Alignment STK32A and SCH9

DIOPT Version :10

• Sequence 1: NP_001274669.1
• Gene: STK32A / 202374
• HGNCID: 28317
• Length: 407
• Species: Homo sapiens
• Sequence 2: NP_012075.1
• Gene: SCH9 / 856612
• SGDID: S000001248
• Length: 824
• Species: Saccharomyces cerevisiae
• Alignment Length: 441
• Identity: 139/441 - (31%)
• Similarity: 220/441 - (49%)
• Gaps: 65/441 - (14%)

Human     6 SRKPPVFDE--NEDVNF--------------DHFEILRAIGKGSFGKVCIVQKNDTKKMYAMKYM 54
            |.||.|.||  :.|:..              ..||:||.:|||:||:|..|:|.||:::||||.:
Yeast   379 SLKPRVIDEVVSGDILIKWTYKQTKKRHYGPQDFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVL 443

Human    55 NKQKCVERNEVRNVFKELQIM---QGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNV 116
            :|:..|::||:.:...|..|:   .....||:|.|.:|||...|:::|.|.:.||:|.:|||:..
Yeast   444 SKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEG 508

Human   117 HFKEETVKLFICELVMALDYLQNQRIIHRDMKPDNILLDEHGHVHITDFNIA-AMLPRETQITTM 180
            .|.|:..|.:|.|||:||::|.:..|::||:||:|||||.:|::.:.||.:: |.|...|  .|.
Yeast   509 RFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRT--NTF 571

Human   181 AGTKPYMAPEMFSSRKGAGYSFAVDWWSLGVTAYELLRGRRPYHIRSSTSSKEIVHTFETTVVTY 245
            .||..|:|||:....  .||:..||:|||||..:|:..|..|:.   :.:::::........|.:
Yeast   572 CGTTEYLAPELLLDE--TGYTKMVDFWSLGVLIFEMCCGWSPFF---AENNQKMYQKIAFGKVKF 631

Human   246 P-SAWSQEMVSLLKKLLEPNPDQRFSQLSD---VQNFPYMNDINWDAVFQKRLIPGFIPN----K 302
            | ...|||..|.:|.||..||..|...:.|   ::..|:..||:|:|:.||::.|.|.|:    .
Yeast   632 PRDVLSQEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFADIDWEALKQKKIPPPFKPHLVSET 696

Human   303 GRLNCDPTF--------ELEEMILESKPLHKKKKRLAKKEKDMRKCDSSQTCLLQEHLDSVQK-- 357
            ...|.||.|        ...:.::.:.||   ...:..|.......|.|   .:.||:::.:|
Yeast   697 DTSNFDPEFTTASTSYMNKHQPMMTATPL---SPAMQAKFAGFTFVDES---AIDEHVNNNRKFL 755

Human   358 ---------EFIIFN-----REKVNRDFNKRQPNLALEQTKDPQVTNGQMD 394
                     .||..|     .|.|..|......|....|.|:...::.|||
Yeast   756 QNSYFMEPGSFIPGNPNLPPDEDVIDDDGDEDINDGFNQEKNMNNSHSQMD 806

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STK32A	NP_001274669.1	STKc_Yank1	22..281	CDD:270730	99/266 (37%)
SCH9	NP_012075.1	YPK1_N_like	181..407	CDD:212165	7/27 (26%)
		STKc_Sck1_like	418..738	CDD:270738	111/329 (34%)