Protein Alignment STK32A and YPK1

DIOPT Version :10

• Sequence 1: NP_001274669.1
• Gene: STK32A / 202374
• HGNCID: 28317
• Length: 407
• Species: Homo sapiens
• Sequence 2: NP_012796.1
• Gene: YPK1 / 853733
• SGDID: S000001609
• Length: 680
• Species: Saccharomyces cerevisiae
• Alignment Length: 359
• Identity: 117/359 - (32%)
• Similarity: 194/359 - (54%)
• Gaps: 42/359 - (11%)

Human     8 KPPVFDENEDVNFDHFEILRAIGKGSFGKVCIVQKNDTKKMYAMKYMNKQKCVERNEVRNVFKEL 72
            ||   ..|:.::.|.|::|:.|||||||||..|:|.||:|:||:|.:.|...|.::||.:...|.
Yeast   335 KP---SRNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAER 396

Human    73 QIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFKEETVKLFICELVMALDYL 137
            .::..::.||:|.|.:|||..|.::.|:..:.||:|.||||:...|.....:.:..||:.|||.|
Yeast   397 TVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNL 461

Human   138 QNQRIIHRDMKPDNILLDEHGHVHITDFNIAAMLPRETQIT-TMAGTKPYMAPEMFSSRKGAGYS 201
            ....:::||:||:|||||..||:.:.||.:..:..::...| |..||..|:|||:.   .|.||:
Yeast   462 HKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELL---LGLGYT 523

Human   202 FAVDWWSLGVTAYELLRGRRPYHIRSSTSSKEIVHTFETTV---VTYPSAWSQEMVSLLKKLLEP 263
            .|||||:|||..||:|.|..||:      .:::...::..:   :.:|..:.::...||..||..
Yeast   524 KAVDWWTLGVLLYEMLTGLPPYY------DEDVPKMYKKILQEPLVFPDGFDRDAKDLLIGLLSR 582

Human   264 NPDQR--FSQLSDVQNFPYMNDINWDAVFQKRLIPGFIPNKGRLNCDPTFELEEMILESKPLHKK 326
            :|.:|  ::...:::|.|:.:.::|..:..|..||.:.|...  |...|...:|.....||:
Yeast   583 DPTRRLGYNGADEIRNHPFFSQLSWKRLLMKGYIPPYKPAVS--NSMDTSNFDEEFTREKPI--- 642

Human   327 KKRLAKKEKDMRKCDSSQTCLLQEHL-DSVQKEF 359
                          ||    ::.|:| :||||:|
Yeast   643 --------------DS----VVDEYLSESVQKQF 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STK32A	NP_001274669.1	STKc_Yank1	22..281	CDD:270730	94/264 (36%)
YPK1	NP_012796.1	YPK1_N_like	116..342	CDD:212165	3/9 (33%)
		Protein Kinases, catalytic domain	352..663	CDD:473864	111/339 (33%)