Protein Alignment TAPT1 and CG7218

DIOPT Version :10

• Sequence 1: NP_699196.2
• Gene: TAPT1 / 202018
• HGNCID: 26887
• Length: 567
• Species: Homo sapiens
• Sequence 2: NP_650678.1
• Gene: CG7218 / 42165
• FlyBaseID: FBgn0038569
• Length: 676
• Species: Drosophila melanogaster
• Alignment Length: 552
• Identity: 237/552 - (42%)
• Similarity: 336/552 - (60%)
• Gaps: 71/552 - (12%)

Human    27 GEAEQPGGSGGQGPPPAPQLTETLGFYESDRRRERRRGRTELSLLRFLSAELTRGYFLEHNEAKY 91
            |.|:|...||     .|...|.|  ||:                  |...|:||||.|||:|.:|
  Fly    58 GSAQQRLQSG-----TAETCTNT--FYD------------------FFKVEMTRGYMLEHDEERY 97

Human    92 TERRERVYTCLRIPRELEKLMVFGIFLCLDAFLYVFTLLPLRVFLALFRLLT---LPCYGLRD-- 151
            :.||:::|:.:||||:||:.||:||..|.|:|||:.|.||:|..:|::.|::   ...:.||.
  Fly    98 SARRQKIYSFMRIPRDLERFMVYGIMQCADSFLYIHTFLPVRFVMAVWALVSRTVARIFRLRSSG 162

Human   152 RRLLQPAQVCDILKGVILVICYFMMHYVDYSMMYHLIRGQSVIKLYIIYNMLEVADRLFSSFGQD 216
            :|||.||::||:|||||.:....:|..||.:.:||:|:.||:|||||.||||||.|||.|:||||
  Fly   163 QRLLSPAEICDLLKGVIWMTVTLIMLLVDTNRVYHIIKSQSIIKLYIFYNMLEVGDRLLSAFGQD 227

Human   217 ILDALYWTATEPKERKRAHIGVIPHFFMAVLYVFLHAILIMVQATTLNVAFNSHNKSLLTIMMSN 281
            .:|||:|||||||..||.|.||:.|....::|||||:.|||.|||.||||.||:||.|||||:||
  Fly   228 TIDALFWTATEPKNSKREHFGVLTHVLFTLIYVFLHSGLIMFQATCLNVAVNSNNKGLLTIMISN 292

Human   282 NFVEIKGSVFKKFEKNNLFQMSNSDIKERFTNYVLLLIVCLRNMEQFSWNPDHLWVLFPDVCMVI 346
            ||||:||||||||:||||||::.||::|||...|||.||.::.|::|.|:.....|:.||...|:
  Fly   293 NFVELKGSVFKKFDKNNLFQLTCSDVRERFHLSVLLFIVVIQTMKEFDWSITQFCVMLPDCFAVL 357

Human   347 ASEIAVDIVKHAFITKFNDITADVYSEYRASLAFDLVSSRQKNAYTDYSDSVARRMGFIPLPLAV 411
            .:||.:|.|||||||:||::...:|.||..|||:|:..:|||:|::|:||.|||||||||.||||
  Fly   358 FTEILIDWVKHAFITRFNELPESIYREYTTSLAYDMTQTRQKHAFSDHSDLVARRMGFIPFPLAV 422

Human   412 LLIRVVTSSIKVQGILSYACVILFYFGLISLKVLNSIVLLGKSCQYVKEAKMEEKLSNP------ 470
            :||:.:.:::..:.:.::...:|.|...:.|::..:|..|||:|:.:||.:.|...|.|
  Fly   423 VLIKAIYTAVSFENLAAWLLFLLAYLFAMGLRICLTICALGKACKLMKEHQTERNSSTPSSMTNV 487

Human   471 ---------PATCTPGKPSSKSQNKCKPSQGLSTEENLSASITKQPIHQKENIIPLLVTSNSDQF 526
                     .|..|.|:..:.:.|          ..|.|.||..:|..         ||:    .
  Fly   488 PVIGAAAPVSAAATGGQNHNNNNN----------NNNNSISIGSKPAQ---------VTT----L 529

Human   527 LTTPDGDEKDITQDNSELKHRSS---KKDLLE 555
            ||.|.....|::::.|.....|:   ||.:.|
  Fly   530 LTPPSAGHLDVSKNFSRTSIASTSTPKKAVSE 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TAPT1	NP_699196.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..60		10/32 (31%)
		DUF747	155..459	CDD:398815	163/303 (54%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	466..499		6/47 (13%)
CG7218	NP_650678.1	DUF747	166..470	CDD:398815	163/303 (54%)