Protein Alignment EN1 and bap

DIOPT Version :10

• Sequence 1: NP_001417.3
• Gene: EN1 / 2019
• HGNCID: 3342
• Length: 392
• Species: Homo sapiens
• Sequence 2: NP_732637.1
• Gene: bap / 42537
• FlyBaseID: FBgn0004862
• Length: 382
• Species: Drosophila melanogaster
• Alignment Length: 277
• Identity: 64/277 - (23%)
• Similarity: 95/277 - (34%)
• Gaps: 83/277 - (29%)

Human   102 TTNFFIDNIL---RPD---FGCKKEQPPPQLLVAAAARGGAGGGGRVERDRGQTAAGRDPVHPLG 160
            ||.|.|::||   .|:   ......:|.|:.|             :...||.::.:...|
  Fly    21 TTPFSINDILTRSNPETRRMSSVDSEPEPEKL-------------KPSSDRERSISKSPP----- 67

Human   161 TRAPGAASLLCAPDANCGPPDGSQPAAAGAGASKAGNPAAAAAAAAAAVAAAAAAAAAKPSDTGG 225
                     ||..|               .|..|...|.....:|..........|||..::...
  Fly    68 ---------LCCRD---------------LGLYKLTQPKEIQPSARQPSNYLQYYAAAMDNNNHH 108

Human   226 GGSGGGAGSPGAQGTKYPEHGNPAILLMGSANGGPV---------VKTDSQQPLVWPAWVYCTRY 281
            ..:.|.:.|..|      ::....:...||....|:         ...||..||
  Fly   109 HQATGTSNSSAA------DYMQRKLAYFGSTLAAPLDMRRCTSNDSDCDSPPPL----------- 156

Human   282 SDRPSSGPRTRK---LKKKKNEKEDKRPRTAFTAEQLQRLKAEFQANRYITEQRRQTLAQELSLN 343
            |..||..|.:..   |.:|      ||.|.||:..|:..|:..|...||::...|..:|:.|.|.
  Fly   157 SSSPSESPLSHDGSGLSRK------KRSRAAFSHAQVFELERRFAQQRYLSGPERSEMAKSLRLT 215

Human   344 ESQIKIWFQNKRAKIKK 360
            |:|:||||||:|.|.|:
  Fly   216 ETQVKIWFQNRRYKTKR 232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EN1	NP_001417.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..100
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	132..164		3/31 (10%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	219..251		3/31 (10%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	282..306		7/26 (27%)
		Homeodomain	305..360	CDD:459649	23/54 (43%)
		Engrail_1_C_sig	361..391	CDD:431338	64/277 (23%)
bap	NP_732637.1	Homeodomain	176..232	CDD:459649	24/55 (44%)