Protein Alignment SPNS3 and DAL5

DIOPT Version :10

• Sequence 1: NP_872344.3
• Gene: SPNS3 / 201305
• HGNCID: 28433
• Length: 512
• Species: Homo sapiens
• Sequence 2: NP_012686.3
• Gene: DAL5 / 853617
• SGDID: S000003913
• Length: 543
• Species: Saccharomyces cerevisiae
• Alignment Length: 282
• Identity: 57/282 - (20%)
• Similarity: 92/282 - (32%)
• Gaps: 114/282 - (40%)

Human    36 SWSLPPWRA--YVAAAVLCYINLLNYMNW------------------------------------ 62
            |:::..||.  .:...:..:|.:|.:: |
Yeast   241 SYAIKGWRTLFVITGVITIFIGILIFL-WIPDDPSKARFLSKREKLMVVQRIRSNQQGFGNHEIK 304

Human    63 -FIIAGVLLDIQE----VFQISDN--HAGLLQTVFVSCLLLSAPVFGYLGDRHSRKATM------ 114
             :.|...|.|::.    :|.:|.|  :.|:  :.|:|.||.|.  |||     |.|.|:
Yeast   305 KYQIIEALKDVRTWLYFLFTVSSNIPNGGI--SSFMSILLNSD--FGY-----SSKETLLMGLPT 360

Human   115 ---------SFGILLWSGAGLSSSFISPRYSWLFFLSRGIVGTGSASYSTIAPTVLGDLFVRDQR 170
                     .||||....|.....|...:.||..|         :|..:.||..:||  |..:.:
Yeast   361 GAVELVGCPLFGILAVYAANKKIPFWKYKLSWAIF---------AAVLALIASCMLG--FATNSK 414

Human   171 TRVLAVFYI-------FIPVGSGL-----GY----------VLGSAVTMLTGNWRWALRVMP--- 210
            ...||..|:       ||.|.|.:     ||          ::..|...|.|...:..:..|
Yeast   415 KARLAGAYLWYISPVSFICVLSNISANSSGYSKKWTVSSINLVAYAAANLAGPQTFIAKQAPKYH 479

Human   211 --------CLEAVALILLILLV 224
                    |...:.::|.|||:
Yeast   480 GAKVAMVVCYAVMIVLLSILLI 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPNS3	NP_872344.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30
		MFS_spinster_like	49..465	CDD:340886	54/267 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	481..512
DAL5	NP_012686.3	MFS_FEN2_like	80..496	CDD:340885	53/275 (19%)