Protein Alignment SPNS3 and Spns3

DIOPT Version :10

• Sequence 1: NP_872344.3
• Gene: SPNS3 / 201305
• HGNCID: 28433
• Length: 512
• Species: Homo sapiens
• Sequence 2: NP_084208.1
• Gene: Spns3 / 77577
• MGIID: 1924827
• Length: 514
• Species: Mus musculus
• Alignment Length: 514
• Identity: 407/514 - (79%)
• Similarity: 439/514 - (85%)
• Gaps: 8/514 - (1%)

Human     5 MSAECPEPGPGGLQGQSPGPGRQ--------CPPPITPTSWSLPPWRAYVAAAVLCYINLLNYMN 61
            ||.||.:|..||.|.||...|.|        |.||.||..||||.||||:|||||||||||||||
Mouse     1 MSTECLKPQTGGPQSQSLSQGGQYGALASGTCLPPSTPVPWSLPRWRAYLAAAVLCYINLLNYMN 65

Human    62 WFIIAGVLLDIQEVFQISDNHAGLLQTVFVSCLLLSAPVFGYLGDRHSRKATMSFGILLWSGAGL 126
            ||||.|||||:|:.|.|||:|||||||||:||||:|||||||||||::|||.:||||||||||||
Mouse    66 WFIIPGVLLDVQKYFHISDSHAGLLQTVFISCLLVSAPVFGYLGDRYNRKAILSFGILLWSGAGL 130

Human   127 SSSFISPRYSWLFFLSRGIVGTGSASYSTIAPTVLGDLFVRDQRTRVLAVFYIFIPVGSGLGYVL 191
            ||||||.:||||||||||.||||:||||||||||||||||:||||..||||||||||||||||||
Mouse   131 SSSFISYQYSWLFFLSRGFVGTGAASYSTIAPTVLGDLFVKDQRTCALAVFYIFIPVGSGLGYVL 195

Human   192 GSAVTMLTGNWRWALRVMPCLEAVALILLILLVPDPPRGAAETQGEGAVGGFRSSWCEDVRYLGK 256
            ||.|..||||||||||:||||:|:||.||||||||.||||||.|||.||...||||||||||||:
Mouse   196 GSTVAELTGNWRWALRLMPCLDAMALALLILLVPDVPRGAAEKQGEVAVRAPRSSWCEDVRYLGR 260

Human   257 NWSFVWSTLGVTAMAFVTGALGFWAPKFLLEARVVHGLQPPCFQEPCSNPDSLIFGALTIMTGVI 321
            |||||:|||||||:|||||||||||||||.|||||||||.|||||.|.:.|||||||||:.||:|
Mouse   261 NWSFVFSTLGVTAIAFVTGALGFWAPKFLFEARVVHGLQLPCFQEQCHSQDSLIFGALTVATGII 325

Human   322 GVILGAEAARRYKKVIPGAEPLICASSLLATAPCLYLALVLAPTTLLASYVFLGLGELLLSCNWA 386
            ||:|||||:||||||.|.||||||||||.||||||||||:||..|||||||||.|||||||||||
Mouse   326 GVMLGAEASRRYKKVNPRAEPLICASSLFATAPCLYLALILASRTLLASYVFLALGELLLSCNWA 390

Human   387 VVADILLSVVVPRCRGTAEALQITVGHILGDAGSPYLTGLISSVLRARRPDSYLQRFRSLQQSFL 451
            |||||||||||||||||||||||||.|:|||||||||||||||||:|.|||||||.|.|||.|||
Mouse   391 VVADILLSVVVPRCRGTAEALQITVAHVLGDAGSPYLTGLISSVLQAERPDSYLQHFLSLQHSFL 455

Human   452 CCAFVIALGGGCFLLTALYLERDETRAWQPVTGTPDSNDVDSNDLERQGLLSGAGASTE 510
            ||||.|.||||.||||||:||:|:.||.||..||.||.|:.|.:.|.||||||....||
Mouse   456 CCAFAIVLGGGFFLLTALHLEKDQARARQPGKGTLDSKDIASRNTESQGLLSGTSTPTE 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPNS3	NP_872344.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30		13/32 (41%)
		MFS_spinster_like	49..465	CDD:340886	352/415 (85%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	481..512		16/30 (53%)
Spns3	NP_084208.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		10/20 (50%)
		MFS_spinster_like	53..469	CDD:340886	352/415 (85%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	482..514		16/31 (52%)