Protein Alignment SPNS3 and Spns3

DIOPT Version :10

• Sequence 1: NP_872344.3
• Gene: SPNS3 / 201305
• HGNCID: 28433
• Length: 512
• Species: Homo sapiens
• Sequence 2: XP_006246848.1
• Gene: Spns3 / 497946
• RGDID: 1561884
• Length: 514
• Species: Rattus norvegicus
• Alignment Length: 514
• Identity: 406/514 - (78%)
• Similarity: 438/514 - (85%)
• Gaps: 8/514 - (1%)

Human     5 MSAECPEPGPGGLQGQSPGPGRQ--------CPPPITPTSWSLPPWRAYVAAAVLCYINLLNYMN 61
            ||.||.:|..||.|.||..||.|        |.||.|..|||||.||||:|||||||:|||||||
  Rat     1 MSRECIKPQTGGPQSQSLSPGGQYGALASGNCLPPSTSASWSLPRWRAYLAAAVLCYVNLLNYMN 65

Human    62 WFIIAGVLLDIQEVFQISDNHAGLLQTVFVSCLLLSAPVFGYLGDRHSRKATMSFGILLWSGAGL 126
            ||||.|||||:|:.|.|||:|||||||||:.|||:|||||||||||:||||.:|||:||||||||
  Rat    66 WFIIPGVLLDVQKYFHISDSHAGLLQTVFIGCLLVSAPVFGYLGDRYSRKAILSFGVLLWSGAGL 130

Human   127 SSSFISPRYSWLFFLSRGIVGTGSASYSTIAPTVLGDLFVRDQRTRVLAVFYIFIPVGSGLGYVL 191
            ||||||.:|||||||||||||||:||||||||||||||||:||||..||||||||||||||||||
  Rat   131 SSSFISYQYSWLFFLSRGIVGTGAASYSTIAPTVLGDLFVKDQRTCALAVFYIFIPVGSGLGYVL 195

Human   192 GSAVTMLTGNWRWALRVMPCLEAVALILLILLVPDPPRGAAETQGEGAVGGFRSSWCEDVRYLGK 256
            ||.|..||||||||||:||||:||||.||||||||.||||||.|||..|...||||.|||||||:
  Rat   196 GSTVAELTGNWRWALRIMPCLDAVALALLILLVPDLPRGAAEKQGEVPVRAPRSSWYEDVRYLGR 260

Human   257 NWSFVWSTLGVTAMAFVTGALGFWAPKFLLEARVVHGLQPPCFQEPCSNPDSLIFGALTIMTGVI 321
            |||||:|||||||:|||||||||||||||.|||||||||.|||||.|.:.|||||||||:.||:|
  Rat   261 NWSFVFSTLGVTAIAFVTGALGFWAPKFLFEARVVHGLQLPCFQEQCHSQDSLIFGALTVATGII 325

Human   322 GVILGAEAARRYKKVIPGAEPLICASSLLATAPCLYLALVLAPTTLLASYVFLGLGELLLSCNWA 386
            ||:|||||:|:||||.|.||||||||||.||||||||||:||..|||||||||.|||||||||||
  Rat   326 GVMLGAEASRKYKKVNPRAEPLICASSLFATAPCLYLALILASRTLLASYVFLALGELLLSCNWA 390

Human   387 VVADILLSVVVPRCRGTAEALQITVGHILGDAGSPYLTGLISSVLRARRPDSYLQRFRSLQQSFL 451
            |||||||||||||||||||||||||.|:|||||||||||||||||:|.||:||||.|.|||.|||
  Rat   391 VVADILLSVVVPRCRGTAEALQITVAHVLGDAGSPYLTGLISSVLQAERPNSYLQHFLSLQHSFL 455

Human   452 CCAFVIALGGGCFLLTALYLERDETRAWQPVTGTPDSNDVDSNDLERQGLLSGAGASTE 510
            ||||.|.|||||||||||:||||:.||.||...|.||.|:...|.||||||||....||
  Rat   456 CCAFAIVLGGGCFLLTALHLERDQARARQPGEETLDSKDIARRDTERQGLLSGTSTPTE 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPNS3	NP_872344.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30		14/32 (44%)
		MFS_spinster_like	49..465	CDD:340886	349/415 (84%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	481..512		16/30 (53%)
Spns3	XP_006246848.1	MFS_spinster_like	53..469	CDD:340886	349/415 (84%)