Protein Alignment CEP112 and CG31998

DIOPT Version :10

• Sequence 1: NP_001340058.1
• Gene: CEP112 / 201134
• HGNCID: 28514
• Length: 956
• Species: Homo sapiens
• Sequence 2: NP_726548.1
• Gene: CG31998 / 43774
• FlyBaseID: FBgn0051998
• Length: 1459
• Species: Drosophila melanogaster
• Alignment Length: 618
• Identity: 114/618 - (18%)
• Similarity: 212/618 - (34%)
• Gaps: 158/618 - (25%)

Human   301 LYRSKQHETEETIRKLEKKVQTLIRDCQVIRETKEDQIAELKKICEQSTESL------------- 352
            :|.|.:|.:...:..|:...|..:|..::...|....:|.||...|..:.|.
  Fly   865 IYISCRHTSIVDVDWLQWGYQFSLRLIEIAIITLMSWVAGLKTSVEHDSLSAVAGDVRMIGSGMG 929

Human   353 ---------NNDWEKK-------LHNA---------VAEMEQEKFDLQ---------KQHTENIQ 383
                     ||...:|       .||:         .:...||.|:..         ..||..::
  Fly   930 AYGQDGGTPNNAIREKHVGNGTGTHNSNVTNFFLPCTSSSSQEHFETDYPAVCNANTNLHTYTMR 994

Human   384 --ELLEDTNVRLNKMESEYMAQTQSTNHMIKELEARVQQL-------TGEAENSNLQRQKLIQEK 439
              :|:.|.:..||.     |..|.:|....:..|.::|:.       ||...::..|:.:|.|.:
  Fly   995 TGKLIYDDSYALNS-----MGPTTATTSNARPCEYQLQEPMYQRPYDTGSIGSTLNQQHQLNQMR 1054

Human   440 AELERCYQ----ITCSELQEVKARRNTLHK-EKDHLVNDYEQNMKLLQTKYDADINLLKQEHALS 499
            .:....|.    :|.|.....:....:||. ..:....||:||    :..::::...|:|:..|.
  Fly  1055 FQEHPTYMSTDYMTDSGPDHYENPNFSLHSTATEQKRRDYDQN----EVSFNSNSGALQQQVELL 1115

Human   500 ASKASSMIEELEQ-------NVCQ---LKQQLQESELQRKQQLRDQENKFQMEKSHL-----KHI 549
            .:...|  |.|||       |:.:   .|::...:.....:.::|::......|...     :|:
  Fly  1116 QNNCYS--EPLEQENKRYEFNIFERPVFKEKSVHNVQSNSECIQDRQKITNGRKKKFNGALDRHV 1178

Human   550 YEKKAHDLQSELDKGKEDTQK--------KIHKFEEALKE---KEEQLTRVTEVQRL-QAQQADA 602
            :|.|.|:.:|........:..        ..:.||.....   |...::.:.:...| :..::..
  Fly  1179 FESKTHERRSSNSANSCSSSNLGGGGRFGSFNSFERGYFNGVCKSGTISSIAKAGALGRTLESPI 1243

Human   603 ALEEFKRQVELNSEKVYAEMKEQMEKVEADLTRSKSLREKQSKEFLWQLEDIRQRYEQQIVELKL 667
            |..|.:|.|...|:.:....|::.:..:....|:.:||..:|:..|::...||:.:.||   |..
  Fly  1244 ASAETQRIVANGSQTLGIPDKDRPQYYQRASGRNSNLRSLESETELFKSMPIRENHLQQ---LPY 1305

Human   668 EHEQEKTHLLQQHNAEKDSLVRDHEREIENLEKQLRAANMEH----------ENQIQEFKKRD-- 720
            .|..|      ....|:|..:..:..|..||      .|.:|          .|.|....|..
  Fly  1306 GHNSE------DEEDEEDDTISGNNVECTNL------INNDHGFVIPVEDTAPNSISMNTKTPSL 1358

Human   721 ----AQVIADMEAQVH-----KLREELINVNS----------------QRKQQLVELGLLREEEK 760
                |...::..||:|     |.|.||...:|                .....:.:.|.||
  Fly  1359 AGSAATKNSNYRAQLHMPNNGKHRSELCTTSSASVASASSNSCTTSSASDSMLVADQGFLR---- 1419

Human   761 QRATREHEIVVNKLKAESEK---MKIELKKTHA 790
            .|:..:...|.|....:||:   :.:.||...|
  Fly  1420 FRSIDDPNCVQNGSNVDSERTAVLSLRLKSCSA 1452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CEP112	NP_001340058.1	DUF4485	13..98	CDD:464345
		Smc	302..>934	CDD:440809	114/617 (18%)
CG31998	NP_726548.1	None