DRSC/TRiP Functional Genomics Resources

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Protein Alignment CEP112 and Uch

DIOPT Version :10

Sequence 1:NP_001340058.1 Gene:CEP112 / 201134 HGNCID:28514 Length:956 Species:Homo sapiens
Sequence 2:NP_476940.1 Gene:Uch / 33397 FlyBaseID:FBgn0010288 Length:227 Species:Drosophila melanogaster


Alignment Length:243 Identity:52/243 - (21%)
Similarity:96/243 - (39%) Gaps:67/243 - (27%)


- Green bases have known domain annotations that are detailed below.


Human   185 PKICEVYSKKSPVSLDDSDIEARLNSWN----LGIEN------PRYLRQKPIPVSLQMTPKFSLR 239
            |::...|..|..||          .:|:    :|:|:      ||     |:...:.:.|     
  Fly    11 PEVLTKYIHKLGVS----------PAWSVTDVIGLEDDTLEWIPR-----PVKAFILLFP----- 55

Human   240 KSSSFHDDHFLSRIREKELDMKTKMMEAKFHEEKLKLQQ-KHDAD-----VQKILERKNNEIEE- 297
             .|..::.|     |.:|.| :.|.:|.:..|:...::| .|:|.     :..:...|..:|:. 
  Fly    56 -CSETYEKH-----RAEEHD-RIKEVEEQHPEDLFYMRQFTHNACGTVALIHSVANNKEVDIDRG 113

Human   298 -LKT-LYRSKQHETEETIRKLEKKVQTLIRDCQVIRETKEDQIAELKKICEQSTESLNNDWEKKL 360
             ||. |.::.....||..|.|||. :....|.:.:.:             |..|.:.|:  ||.:
  Fly   114 VLKDFLEKTASLSPEERGRALEKD-EKFTADHEALAQ-------------EGQTNAANH--EKVI 162

Human   361 HNAVAEMEQE----KFDLQKQHTENIQELLEDTNVR-LNKMESEYMAQ 403
            |:.:|.:.:|    :.|.:|..........|:|.|: ..|:..|:||:
  Fly   163 HHFIALVNKEGTLYELDGRKSFPIKHGPTSEETFVKDAAKVCKEFMAR 210

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CEP112NP_001340058.1 DUF4485 13..98 CDD:464345
Smc 302..>934 CDD:440809 24/107 (22%)
UchNP_476940.1 Peptidase_C12_UCH_L1_L3 4..222 CDD:187737 52/243 (21%)
Blue background indicates that the domain is not in the aligned region.

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