DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ELK4 and Ets96B

DIOPT Version :9

Sequence 1:	NP_001964.2	Gene:	ELK4 / 2005	HGNCID:	3326	Length:	431	Species:	Homo sapiens
Sequence 2:	NP_996290.1	Gene:	Ets96B / 42952	FlyBaseID:	FBgn0039225	Length:	640	Species:	Drosophila melanogaster

Alignment Length:	154	Identity:	63/154 - (40%)
Similarity:	88/154 - (57%)	Gaps:	16/154 - (10%)

- Green bases have known domain annotations that are detailed below.

Human     4 AITLWQFLLQLLQKP-QNKHMICWTSNDGQFKLLQAEEVARLWGIRKNKPNMNYDKLSRALRYYY 67
            ::.|||||:.||.:| .:...|.||....:|||::.|||||.||::||:|.||||||||:|||||
  Fly   497 SLQLWQFLVALLDEPTTSASCIAWTGRGMEFKLIEPEEVARRWGLQKNRPAMNYDKLSRSLRYYY 561

Human    68 VKNIIKKVNGQKFVYKFVSYPEIL-NM--DPMTVGRIEGDCESLNFSEVSSSSKDVENGGKDKPP 129
            .|.|::||||:::||:||..|:.| ||  ..:|.|..:||...|..|...:            ||
  Fly   562 EKGIMQKVNGERYVYRFVCDPDALFNMAYGHLTTGSGKGDQHQLTLSLAKT------------PP 614

Human   130 QPGAKTSSRNDYIHSGLYSSFTLN 153
            ..|...:.......|..|.:..|:
  Fly   615 TSGDSQTQSPRVAKSEYYDTAALH 638

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ELK4	NP_001964.2	ETS	17..88	CDD:197710	40/71 (56%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	114..139		3/24 (13%)
		Herpes_DNAp_acc	<237..323	CDD:282746
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	251..282
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	294..323
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	411..431
Ets96B	NP_996290.1	ETS	497..583	CDD:197710	47/85 (55%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3806
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810