DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ELK3 and pnt

DIOPT Version :9

Sequence 1:	NP_005221.2	Gene:	ELK3 / 2004	HGNCID:	3325	Length:	407	Species:	Homo sapiens
Sequence 2:	NP_524461.2	Gene:	pnt / 42757	FlyBaseID:	FBgn0003118	Length:	718	Species:	Drosophila melanogaster

Alignment Length:	109	Identity:	54/109 - (49%)
Similarity:	74/109 - (67%)	Gaps:	4/109 - (3%)

- Green bases have known domain annotations that are detailed below.

Human     5 ITLWQFLLQLLLDQKHEHLICWTSNDGEFKLLKAEEVAKLWGLRKNKTNMNYDKLSRALRYYYDK 69
            |.||||||:||||:..:..|.||.:..||||...:|||:.||:||||..|||:||||.|||||||
  Fly   610 IQLWQFLLELLLDKTCQSFISWTGDGWEFKLTDPDEVARRWGIRKNKPKMNYEKLSRGLRYYYDK 674

Human    70 NIIKKVIGQKFVYKFVSFPEILKMDPHAVE--ISRESLLLQDSD 111
            |||.|..|:::||:||.  ::..:..|..|  :::..|.::..|
  Fly   675 NIIHKTAGKRYVYRFVC--DLQNLVGHTPEELVAKYDLKIEKKD 716

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ELK3	NP_005221.2	ETS	19..88	CDD:197710	39/68 (57%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	234..253
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	271..298
		CTBP-binding motif	273..277
pnt	NP_524461.2	SAM_PNT-ETS-1,2	179..250	CDD:188879
pnt	NP_524461.2	ETS	609..693	CDD:197710	50/84 (60%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3806
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810