Protein Alignment ELK1 and Ets97D

DIOPT Version :10

• Sequence 1: NP_005220.2
• Gene: ELK1 / 2002
• HGNCID: 3321
• Length: 428
• Species: Homo sapiens
• Sequence 2: NP_001263000.1
• Gene: Ets97D / 43236
• FlyBaseID: FBgn0004510
• Length: 484
• Species: Drosophila melanogaster
• Alignment Length: 152
• Identity: 62/152 - (40%)
• Similarity: 79/152 - (51%)
• Gaps: 35/152 - (23%)

Human     1 MDPS------------VTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKT 53
            |:||            |.||||||::|.:..:..:|.|...: |||||.|.:.||||||.:|||.
  Fly   330 MNPSNYTTIGSGNNGQVQLWQFLLEILTDCEHTDVIEWVGTE-GEFKLTDPDRVARLWGEKKNKP 393

Human    54 NMNYDKLSRALRYYYDKNIIRKVSGQKFVYKFVSYPEVAGCSTEDCP-------PQPEVSVTSTM 111
            .|||:|||||||||||.::|.||||::|.|||            ||.       ...|:|...:.
  Fly   394 AMNYEKLSRALRYYYDGDMISKVSGKRFAYKF------------DCDLKLLIGYDANELSTLVSE 446

Human   112 PNVAP---AAIHAAPGDTVSGK 130
            ...||   ||......|| .|:
  Fly   447 GKTAPERVAATETITEDTXHGE 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ELK1	NP_005220.2	ETS	4..89	CDD:197710	49/96 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	121..149		3/10 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	165..205
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	228..358
		Sufficient for interaction with MAD2L2. /evidence=ECO:0000269|PubMed:17296730	349..399
Ets97D	NP_001263000.1	GABP-alpha	48..123	CDD:463311
		SAM_PNT-GABP-alpha	184..272	CDD:176084
		ETS	345..429	CDD:197710	50/96 (52%)