Protein Alignment SLC5A9 and CG33124

DIOPT Version :9

• Sequence 1: XP_011539226.1
• Gene: SLC5A9 / 200010
• HGNCID: 22146
• Length: 719
• Species: Homo sapiens
• Sequence 2: NP_001097056.3
• Gene: CG33124 / 318891
• FlyBaseID: FBgn0053124
• Length: 588
• Species: Drosophila melanogaster
• Alignment Length: 587
• Identity: 128/587 - (21%)
• Similarity: 225/587 - (38%)
• Gaps: 161/587 - (27%)

Human    67 YFLAGRSMSWWPIGASLMSSNVGSGLFIGLAGTGAAGGLAVGGFEWNMRKSRSGGDRGIHPRSHG 131
            |.:....:..:|:..||::|      ||        .|:|:.|                :|
  Fly    61 YLMGSGHLKVFPVAMSLIAS------FI--------SGVAILG----------------NP---- 91

Human   132 RTGVRSQVSYFSVRGPPTAQHCLWVGSRPSVYIQDLDTFFFSPLSQATWLLLALGWVFVPVYIAA 196
                 |::.|:.      .|:.|.|   .::.||.                ||:.::::||:.|.
  Fly    92 -----SEIYYYG------TQYSLIV---LAIVIQG----------------LAVSYIYLPVFSAL 126

Human   197 GVVTMPQYLKKRFGG--QRIQVYMSVLSLILYI-FTKISTDIFSGALFIQMALGWNLYLSTGILL 258
            .|.:..:||..||..  :.|...|.|:.::||. |.     :|..||.:..|.|.|:::...:::
  Fly   127 QVRSSYEYLGMRFHPLIRNIVSIMFVIEVLLYTPFV-----VFVPALALNQASGLNIHMIEVLII 186

Human   259 VVTAVYTIAGGLMAVIYTDALQTVIMVGGALVLMFLGFQDVGWYPGLEQRYRQAI---------- 313
            ||..:||:.|||.||::||..|.|||....:|:..|.   ..:...|:..:...:
  Fly   187 VVCVIYTLLGGLKAVVHTDIWQVVIMFASVVVVAILA---TCYITDLDDFFESLVDGGRLIFGNI 248

Human   314 -PNVTVPNTTCHLPRPDAFH----ILRDPVIVQRSLSAKSLSHAKGG---SVLGGYLKILPMFFI 370
             |:..|.||...:....||:    ......:|.|.:|..:|..|:..   .|||..:     |:.
  Fly   249 NPSPYVRNTVWSVVIGGAFYWTSITAVHQTMVHRYMSLPNLKMARTSIAFFVLGSII-----FYS 308

Human   371 VMP--GMISRALFPDEVGCVDPDVCQRICGARVGCSNIAYPKLVMALMP--VGLRGLMIAVIMAA 431
            |:.  |::...::.|         |..:...::..::...|..|:..:.  .|:.||.||.|..|
  Fly   309 VLSFLGLLIFNMYKD---------CDPLSAGQIMNNDQLVPLFVVQSVGHIYGIPGLFIAGIFGA 364

Human   432 LMSSLTSIFNSSSTLFTIDVWQR-FRRKSTEQELMVVGRVFVVFLVVISILWIPIIQSSNSGQLF 495
            .:|||:...||:|.:...|:.:. |:.:..|....::.:..:|.:..:....:.:::     ::.
  Fly   365 GLSSLSVFLNSTSLVILQDIVRGCFKMQPGETASAIIVKATIVIMGALVFGEVLLLE-----KVS 424

Human   496 DYIQAVTSYLAPPITALFLLAIFCKRVTEPGAFWGLVFGLGVG-----LLRMILEF-SYPAPACG 554
            ..:....|.:|...::.|  .||...|..|   |....|..||     ||...:.| |..|.|.|
  Fly   425 GILSICMSLVAIATSSTF--GIFTLAVLVP---WANTVGTAVGGIAGFLLTGWITFGSQIAAASG 484

Human   555 E------------------------VDRR---PAVLKDFHYLYFAILLCGLTAIVIV--IVSLCT 590
            :                        ||..   |.....||:    |...|...:|:|  :|||.|
  Fly   485 QLHHHRLPVSVASCPGNVTARENVWVDEEQVFPLFRLSFHW----INPIGALTVVVVGSLVSLVT 545

Human   591 TP 592
            .|
  Fly   546 KP 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A9	XP_011539226.1	SLC5-6-like_sbd	37..719	CDD:294310	128/587 (22%)
CG33124	NP_001097056.3	SLC5sbd_NIS-SMVT	9..533	CDD:271383	121/571 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146426
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750