Protein Alignment ARY and KCNAB3

DIOPT Version :10

• Sequence 1: NP_001163844.1
• Gene: ARY / 19988923
• FlyBaseID: FBgn0058064
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: XP_047293000.1
• Gene: KCNAB3 / 9196
• HGNCID: 6230
• Length: 460
• Species: Homo sapiens
• Alignment Length: 206
• Identity: 52/206 - (25%)
• Similarity: 73/206 - (35%)
• Gaps: 63/206 - (30%)

  Fly    45 SGHEMPVLGFGTYKLRGYQCS-----AAVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMGNI 104
            ||..:..||.||:...|.|.|     ..:..|.|.|...||||..|    ..|:|.||   :|||
Human    86 SGLRVSCLGLGTWVTFGSQISDETAEDVLTVAYEHGVNLFDTAEVY----AAGKAERT---LGNI 143

  Fly   105 ------SRENIFLTTKL-WNTHHDPRDVRRICEK--------QLELLGFSYIDLYLM-----HFP 149
                  .|.:..:|||: |....:..  |.:..|        .||.|...|:|:...     :.|
Human   144 LKSKGWRRSSYVITTKIFWGGQAETE--RGLSRKHIIEGLRGSLERLQLGYVDIVFANRSDPNCP 206

  Fly   150 VGYKYVCDEILMPMSGDELQTVEIDYLDTWRAMENLVKLGMVRSIGLSNFN----MEQIQRIIQC 210
            :      :||:                   |||..::..|:....|.|.:.    ||......|.
Human   207 M------EEIV-------------------RAMTYVINQGLALYWGTSRWGAAEIMEAYSMARQF 246

  Fly   211 SSSKPVVNQVE 221
            :...||..|.|
Human   247 NLIPPVCEQAE 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ARY	NP_001163844.1	AKR_AKR2E1-5	39..331	CDD:381342	52/206 (25%)
KCNAB3	XP_047293000.1	AKR_SF	76..349	CDD:444925	52/206 (25%)