Protein Alignment ARY and GRE3

DIOPT Version :10

• Sequence 1: NP_001163844.1
• Gene: ARY / 19988923
• FlyBaseID: FBgn0058064
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_011972.1
• Gene: GRE3 / 856504
• SGDID: S000001146
• Length: 327
• Species: Saccharomyces cerevisiae
• Alignment Length: 311
• Identity: 104/311 - (33%)
• Similarity: 170/311 - (54%)
• Gaps: 18/311 - (5%)

  Fly    37 MAPKVRLSSGHEMPVLGFGTYKLRGYQCSAAVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKM 101
            |:..|.|::|.:||::|.|.:|:....|:..::.||:.|:|.||.|..|.||||:||.:|..|..
Yeast     1 MSSLVTLNNGLKMPLVGLGCWKIDKKVCANQIYEAIKLGYRLFDGACDYGNEKEVGEGIRKAISE 65

  Fly   102 GNISRENIFLTTKLWNTHHDPRDVRRICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPM--- 163
            |.:||::||:.:||||..|.|..|:...:|.|..:|..|:|||.:|||:.:|||..|...|.
Yeast    66 GLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKYVPFEEKYPPGFY 130

  Fly   164 --SGDE----LQTVEIDYLDTWRAMENLVKLGMVRSIGLSNFNMEQIQRIIQCSSSKPVVNQVEI 222
              :.||    :....:..:||:||:|..|..|:::|||:|||....||.:::....|||..|:|.
Yeast   131 TGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLIQDLLRGCRIKPVALQIEH 195

  Fly   223 WPGFLQKDLVDYCRYNGIIVTAFSPLGQPN-------RKNHCPVYFFSEGMKRLVKKYKRS-ASQ 279
            .|...|:.||::|:.:.|.|.|:|..|..:       .....|..|.::.:|::.:.:..| .||
Yeast   196 HPYLTQEHLVEFCKLHDIQVVAYSSFGPQSFIEMDLQLAKTTPTLFENDVIKKVSQNHPGSTTSQ 260

  Fly   280 IVLRYLIDYGVVPIPKAANPIHIKENLNI-FDFKLDEADTRLLRGIKPKSR 329
            ::||:....|:..|||::....:..||.| ..|.|.|.:.:.:..:....|
Yeast   261 VLLRWATQRGIAVIPKSSKKERLLGNLEIEKKFTLTEQELKDISALNANIR 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ARY	NP_001163844.1	AKR_AKR2E1-5	39..331	CDD:381342	103/309 (33%)
GRE3	NP_011972.1	AKR_SF	3..318	CDD:444925	103/309 (33%)