DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ARY and AKR4C11

DIOPT Version :9

Sequence 1:	NP_001163844.1	Gene:	ARY / 19988923	FlyBaseID:	FBgn0058064	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_190956.1	Gene:	AKR4C11 / 824555	AraportID:	AT3G53880	Length:	315	Species:	Arabidopsis thaliana

Alignment Length:	331	Identity:	105/331 - (31%)
Similarity:	172/331 - (51%)	Gaps:	40/331 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 MAPKV---RLSSGHEMPVLGFGTYKLRGYQCSAAVHCAIETGFRHFDTAYYYENEKEIGEALRTQ 98
            ||.::   :|::|.::|.:|.||::........||..|::.|::|.|.|..|.||.|||:.|:..
plant     1 MADEIGFFQLNTGAKIPSVGLGTWQAAPGVVGDAVAAAVKIGYQHIDCASRYGNEIEIGKVLKKL 65

  Fly    99 IKMGNISRENIFLTTKLWNTHHDPRDVRRICEKQLELLGFSYIDLYLMHFPVGYKY-VCD---EI 159
            ...|.:.||.:|:|:|:|.|..||.||:....:.|:.|...|:||||||:||..|. ..|   |.
plant    66 FDDGVVKREKLFITSKIWLTDLDPPDVQDALNRTLQDLQLDYVDLYLMHWPVRLKKGTVDFKPEN 130

  Fly   160 LMPMSGDELQTVEIDYLDTWRAMENLVKLGMVRSIGLSNFNMEQIQRIIQCSSSKPVVNQVEIWP 224
            :||          ||...||:|||.||..|..|:||:|||:.:::..:::.:...|.|||||..|
plant   131 IMP----------IDIPSTWKAMEALVDSGKARAIGVSNFSTKKLSDLVEAARVPPAVNQVECHP 185

  Fly   225 GFLQKDLVDYCRYNGIIVTAFSPLGQPNRKNHCPVYFFSEGMKRLVKKYKRSASQIVLRYLIDYG 289
            .:.|..|.::|:..||.::.:||||.|...........|..::.:.|:..:|.:|..||:.:..|
plant   186 SWQQHKLHEFCKSKGIHLSGYSPLGSPGTTWVKADVLKSPVIEMIAKEIGKSPAQTALRWGLQMG 250

  Fly   290 VVPIPKAANPIHIKENLNIFDFKLDEADTRLLRGIKPK------SRIVKYEIVKDHMFY-----P 343
            ...:||:.|...|:||.::..:.:            ||      |:|.:..:|:...|.     |
plant   251 HSILPKSTNEGRIRENFDVLGWSI------------PKEMFDKFSKIEQARLVQGTSFVHETLSP 303

  Fly   344 FELLKE 349
            ::.|:|
plant   304 YKTLEE 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ARY	NP_001163844.1	ARA1	37..332	CDD:223729	100/307 (33%)
ARY	NP_001163844.1	Tas	50..324	CDD:223739	92/277 (33%)
AKR4C11	NP_190956.1	AKR_AKR4C1-15	6..292	CDD:381351	98/307 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	1	1.000	-	-		otm2923
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.730