DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ARY and akr1c3

DIOPT Version :9

Sequence 1:	NP_001163844.1	Gene:	ARY / 19988923	FlyBaseID:	FBgn0058064	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_001072181.1	Gene:	akr1c3 / 779627	XenbaseID:	XB-GENE-5821909	Length:	324	Species:	Xenopus tropicalis

Alignment Length:	322	Identity:	115/322 - (35%)
Similarity:	173/322 - (53%)	Gaps:	28/322 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 VRLSSGHEMPVLGFGTYKLRGYQCSAA---VHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMG 102
            |.|:.||:|||:|||||....:..|.|   ...||:.|:||.|.|:.|.||:|:|.|:|.:|..|
Frog     9 VELNDGHKMPVIGFGTYAPPKFPKSLAEEGTKVAIDVGYRHIDCAFLYGNEEEVGRAIRAKIADG 73

  Fly   103 NISRENIFLTTKLWNTHHDPRDVRRICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMSGDE 167
            .:.||::|.|.|||:|.|.|..||...||.|:.|...|:||:::|.|:.:|          .||:
Frog    74 TVKREDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIHMPMEFK----------PGDD 128

  Fly   168 LQTVE---------IDYLDTWRAMENLVKLGMVRSIGLSNFNMEQIQRIIQCS--SSKPVVNQVE 221
            |...:         .|..|||:|:|.....|:|||||:||||.:|::.|:...  ..|||.||||
Frog   129 LFPADENGKFIYHNTDLRDTWKALEKCKDAGLVRSIGVSNFNHKQLELILNMPGLKYKPVCNQVE 193

  Fly   222 IWPGFLQKDLVDYCRYNGIIVTAFSPLGQPNRKN----HCPVYFFSEGMKRLVKKYKRSASQIVL 282
            ......|..|:::|:...|::..:|.||....:.    ..||......:..:.||:.|:.:|:.:
Frog   194 CHVYLNQSKLLEFCKSKDIVLVGYSVLGSSRDERWIEASTPVLLEDPALTEIAKKHNRTPAQVAM 258

  Fly   283 RYLIDYGVVPIPKAANPIHIKENLNIFDFKLDEADTRLLRGIKPKSRIVKYEIVKDHMFYPF 344
            ||.:..|||.:.|:..|..|::|..:|||:||..|.|.:.|:....|.:......||..||:
Frog   259 RYHLQRGVVVLAKSFTPARIQQNFQVFDFQLDAEDMRSIDGLNRNMRYIDTSRWSDHPKYPY 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ARY	NP_001163844.1	ARA1	37..332	CDD:223729	111/308 (36%)
ARY	NP_001163844.1	Tas	50..324	CDD:223739	104/291 (36%)
akr1c3	NP_001072181.1	AKR_AKR1C1-35	8..308	CDD:381334	111/308 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	1	1.000	-	-		mtm9378
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010