Protein Alignment ARY and akr1c3

DIOPT Version :10

• Sequence 1: NP_001163844.1
• Gene: ARY / 19988923
• FlyBaseID: FBgn0058064
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_001072181.1
• Gene: akr1c3 / 779627
• XenbaseID: XB-GENE-5821909
• Length: 324
• Species: Xenopus tropicalis
• Alignment Length: 322
• Identity: 115/322 - (35%)
• Similarity: 173/322 - (53%)
• Gaps: 28/322 - (8%)

  Fly    41 VRLSSGHEMPVLGFGTYKLRGYQCSAA---VHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMG 102
            |.|:.||:|||:|||||....:..|.|   ...||:.|:||.|.|:.|.||:|:|.|:|.:|..|
 Frog     9 VELNDGHKMPVIGFGTYAPPKFPKSLAEEGTKVAIDVGYRHIDCAFLYGNEEEVGRAIRAKIADG 73

  Fly   103 NISRENIFLTTKLWNTHHDPRDVRRICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMSGDE 167
            .:.||::|.|.|||:|.|.|..||...||.|:.|...|:||:::|.|:.:|          .||:
 Frog    74 TVKREDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIHMPMEFK----------PGDD 128

  Fly   168 LQTVE---------IDYLDTWRAMENLVKLGMVRSIGLSNFNMEQIQRIIQCS--SSKPVVNQVE 221
            |...:         .|..|||:|:|.....|:|||||:||||.:|::.|:...  ..|||.||||
 Frog   129 LFPADENGKFIYHNTDLRDTWKALEKCKDAGLVRSIGVSNFNHKQLELILNMPGLKYKPVCNQVE 193

  Fly   222 IWPGFLQKDLVDYCRYNGIIVTAFSPLGQPNRKN----HCPVYFFSEGMKRLVKKYKRSASQIVL 282
            ......|..|:::|:...|::..:|.||....:.    ..||......:..:.||:.|:.:|:.:
 Frog   194 CHVYLNQSKLLEFCKSKDIVLVGYSVLGSSRDERWIEASTPVLLEDPALTEIAKKHNRTPAQVAM 258

  Fly   283 RYLIDYGVVPIPKAANPIHIKENLNIFDFKLDEADTRLLRGIKPKSRIVKYEIVKDHMFYPF 344
            ||.:..|||.:.|:..|..|::|..:|||:||..|.|.:.|:....|.:......||..||:
 Frog   259 RYHLQRGVVVLAKSFTPARIQQNFQVFDFQLDAEDMRSIDGLNRNMRYIDTSRWSDHPKYPY 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ARY	NP_001163844.1	AKR_AKR2E1-5	39..331	CDD:381342	111/307 (36%)
akr1c3	NP_001072181.1	AKR_AKR1C1-35	8..308	CDD:381334	111/308 (36%)