Protein Alignment ARY and AKR1D1

DIOPT Version :10

• Sequence 1: NP_001163844.1
• Gene: ARY / 19988923
• FlyBaseID: FBgn0058064
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_005980.1
• Gene: AKR1D1 / 6718
• HGNCID: 388
• Length: 326
• Species: Homo sapiens
• Alignment Length: 329
• Identity: 123/329 - (37%)
• Similarity: 181/329 - (55%)
• Gaps: 39/329 - (11%)

  Fly    40 KVRLSSGHEMPVLGFGTYK-----LRGYQCSAAVHCAIETGFRHFDTAYYYENEKEIGEALRTQI 99
            ::.||.|:.:|::|.|||.     .:| .|:.:|..||:||:||.|.||.|:||.|:|||:|.:|
Human     9 RIPLSDGNSIPIIGLGTYSEPKSTPKG-ACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKI 72

  Fly   100 KMGNISRENIFLTTKLWNTHHDPRDVRRICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMS 164
            ..|.:.||:||...|||.|:|.|..||...|:.|.:|...|:|||::..|:.:|          .
Human    73 AEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFK----------P 127

  Fly   165 GDELQTVE---------IDYLDTWRAMENLVKLGMVRSIGLSNFNMEQIQRIIQCS--SSKPVVN 218
            |||:...:         .:...||.|||.....|:|:|:|:||||..|::.|:...  ..|||.|
Human   128 GDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSN 192

  Fly   219 QVEIWPGFLQKDLVDYCRYNGIIVTAFSPLGQPNRKNHCPVYFFSEG--------MKRLVKKYKR 275
            |||..|.|.|..|:.:|:.:.|::||:||||....    |::.....        :..|.|:|.:
Human   193 QVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRN----PIWVNVSSPPLLKDALLNSLGKRYNK 253

  Fly   276 SASQIVLRYLIDYGVVPIPKAANPIHIKENLNIFDFKLDEADTRLLRGIKPKSRIVKYEIVKDHM 340
            :|:|||||:.|..|||.|||:.|...||||..||||.|.|.:.:.:..:....|.|:..:.:||.
Human   254 TAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFVELLMWRDHP 318

  Fly   341 FYPF 344
            .|||
Human   319 EYPF 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ARY	NP_001163844.1	AKR_AKR2E1-5	39..331	CDD:381342	117/314 (37%)
AKR1D1	NP_005980.1	AKR_AKR1D1-3	15..322	CDD:381335	119/321 (37%)