Protein Alignment ARY and AKR1D1

DIOPT Version :9

• Sequence 1: NP_001163844.1
• Gene: ARY / 19988923
• FlyBaseID: FBgn0058064
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_005980.1
• Gene: AKR1D1 / 6718
• HGNCID: 388
• Length: 326
• Species: Homo sapiens
• Alignment Length: 329
• Identity: 123/329 - (37%)
• Similarity: 181/329 - (55%)
• Gaps: 39/329 - (11%)

  Fly    40 KVRLSSGHEMPVLGFGTYK-----LRGYQCSAAVHCAIETGFRHFDTAYYYENEKEIGEALRTQI 99
            ::.||.|:.:|::|.|||.     .:| .|:.:|..||:||:||.|.||.|:||.|:|||:|.:|
Human     9 RIPLSDGNSIPIIGLGTYSEPKSTPKG-ACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKI 72

  Fly   100 KMGNISRENIFLTTKLWNTHHDPRDVRRICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMS 164
            ..|.:.||:||...|||.|:|.|..||...|:.|.:|...|:|||::..|:.:|          .
Human    73 AEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFK----------P 127

  Fly   165 GDELQTVE---------IDYLDTWRAMENLVKLGMVRSIGLSNFNMEQIQRIIQCS--SSKPVVN 218
            |||:...:         .:...||.|||.....|:|:|:|:||||..|::.|:...  ..|||.|
Human   128 GDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSN 192

  Fly   219 QVEIWPGFLQKDLVDYCRYNGIIVTAFSPLGQPNRKNHCPVYFFSEG--------MKRLVKKYKR 275
            |||..|.|.|..|:.:|:.:.|::||:||||....    |::.....        :..|.|:|.:
Human   193 QVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRN----PIWVNVSSPPLLKDALLNSLGKRYNK 253

  Fly   276 SASQIVLRYLIDYGVVPIPKAANPIHIKENLNIFDFKLDEADTRLLRGIKPKSRIVKYEIVKDHM 340
            :|:|||||:.|..|||.|||:.|...||||..||||.|.|.:.:.:..:....|.|:..:.:||.
Human   254 TAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFVELLMWRDHP 318

  Fly   341 FYPF 344
            .|||
Human   319 EYPF 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ARY	NP_001163844.1	ARA1	37..332	CDD:223729	117/315 (37%)
		Tas	50..324	CDD:223739	113/297 (38%)
AKR1D1	NP_005980.1	AKR_AKR1D1-3	15..322	CDD:381335	119/321 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.730