Protein Alignment ARY and akr1a1

DIOPT Version :10

• Sequence 1: NP_001163844.1
• Gene: ARY / 19988923
• FlyBaseID: FBgn0058064
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_001016137.1
• Gene: akr1a1 / 548891
• XenbaseID: XB-GENE-1014353
• Length: 327
• Species: Xenopus tropicalis
• Alignment Length: 316
• Identity: 127/316 - (40%)
• Similarity: 181/316 - (57%)
• Gaps: 16/316 - (5%)

  Fly    43 LSSGHEMPVLGFGTYKLRGYQCSAAVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMG-NISR 106
            |.:|.::|::|.||:|....|...||..|:..|:||.|.|:.|.||.|:|||::..:... .:||
 Frog    10 LYTGQKIPLIGLGTWKSAPGQVKDAVKYALGVGYRHIDCAFVYGNETEVGEAIKESVGSDKGLSR 74

  Fly   107 ENIFLTTKLWNTHHDPRDVRRICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMSGD-ELQT 170
            |.:|:|:||||..|.|.||.....|.|:.|...|:||||||:|..:|.  .:.:.|.:.| .:|.
 Frog    75 EEVFVTSKLWNNKHHPDDVECALRKTLQDLQLDYLDLYLMHWPYAFKR--GDQIFPQNPDGSVQY 137

  Fly   171 VEIDYLDTWRAMENLVKLGMVRSIGLSNFNMEQIQRIIQCSSSKPVVNQVEIWPGFLQKDLVDYC 235
            ...||.|||:|||.|||.|:.::|||||||..||..||..::.||.|.|||..|...|.:|:.||
 Frog   138 DLTDYKDTWKAMEKLVKQGLTKAIGLSNFNKRQIDDIISIATVKPAVLQVECHPYLAQNELIAYC 202

  Fly   236 RYNGIIVTAFSPLGQPN---RKNHCPVYFFSEGMKRLVKKYKRSASQIVLRYLIDYGVVPIPKAA 297
            ..:|::.|.:||||.|:   ||...||.....|:..:.|||.:|.:||:||:.:...||.|||:.
 Frog   203 HAHGLVFTGYSPLGSPDRSWRKPEDPVLLEEPGIIAMAKKYGKSEAQILLRWQVQRKVVSIPKSV 267

  Fly   298 NPIHIKENLNIFDFKLDEADTRLL-------RGIKPKSRIVKYEIVKD--HMFYPF 344
            .|..|.:|..:|||.|.|.:.:|:       |.|.|...:....:.:|  |..|||
 Frog   268 TPTRILQNFQVFDFSLSEEEMQLIGALNKNWRYIIPLITVNGKSVPRDAGHPLYPF 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ARY	NP_001163844.1	AKR_AKR2E1-5	39..331	CDD:381342	122/299 (41%)
akr1a1	NP_001016137.1	AKR_AKR1A1-4	10..314	CDD:381332	122/305 (40%)