DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ARY and akr1a1

DIOPT Version :9

Sequence 1:	NP_001163844.1	Gene:	ARY / 19988923	FlyBaseID:	FBgn0058064	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_001016137.1	Gene:	akr1a1 / 548891	XenbaseID:	XB-GENE-1014353	Length:	327	Species:	Xenopus tropicalis

Alignment Length:	316	Identity:	127/316 - (40%)
Similarity:	181/316 - (57%)	Gaps:	16/316 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 LSSGHEMPVLGFGTYKLRGYQCSAAVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMG-NISR 106
            |.:|.::|::|.||:|....|...||..|:..|:||.|.|:.|.||.|:|||::..:... .:||
Frog    10 LYTGQKIPLIGLGTWKSAPGQVKDAVKYALGVGYRHIDCAFVYGNETEVGEAIKESVGSDKGLSR 74

  Fly   107 ENIFLTTKLWNTHHDPRDVRRICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMSGD-ELQT 170
            |.:|:|:||||..|.|.||.....|.|:.|...|:||||||:|..:|.  .:.:.|.:.| .:|.
Frog    75 EEVFVTSKLWNNKHHPDDVECALRKTLQDLQLDYLDLYLMHWPYAFKR--GDQIFPQNPDGSVQY 137

  Fly   171 VEIDYLDTWRAMENLVKLGMVRSIGLSNFNMEQIQRIIQCSSSKPVVNQVEIWPGFLQKDLVDYC 235
            ...||.|||:|||.|||.|:.::|||||||..||..||..::.||.|.|||..|...|.:|:.||
Frog   138 DLTDYKDTWKAMEKLVKQGLTKAIGLSNFNKRQIDDIISIATVKPAVLQVECHPYLAQNELIAYC 202

  Fly   236 RYNGIIVTAFSPLGQPN---RKNHCPVYFFSEGMKRLVKKYKRSASQIVLRYLIDYGVVPIPKAA 297
            ..:|::.|.:||||.|:   ||...||.....|:..:.|||.:|.:||:||:.:...||.|||:.
Frog   203 HAHGLVFTGYSPLGSPDRSWRKPEDPVLLEEPGIIAMAKKYGKSEAQILLRWQVQRKVVSIPKSV 267

  Fly   298 NPIHIKENLNIFDFKLDEADTRLL-------RGIKPKSRIVKYEIVKD--HMFYPF 344
            .|..|.:|..:|||.|.|.:.:|:       |.|.|...:....:.:|  |..|||
Frog   268 TPTRILQNFQVFDFSLSEEEMQLIGALNKNWRYIIPLITVNGKSVPRDAGHPLYPF 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ARY	NP_001163844.1	ARA1	37..332	CDD:223729	122/300 (41%)
ARY	NP_001163844.1	Tas	50..324	CDD:223739	118/285 (41%)
akr1a1	NP_001016137.1	AKR_AKR1A1-4	10..314	CDD:381332	122/305 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.930