Protein Alignment ARY and Akr1c12l1

DIOPT Version :10

• Sequence 1: NP_001163844.1
• Gene: ARY / 19988923
• FlyBaseID: FBgn0058064
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_001129216.1
• Gene: Akr1c12l1 / 498790
• RGDID: 1559604
• Length: 323
• Species: Rattus norvegicus
• Alignment Length: 325
• Identity: 121/325 - (37%)
• Similarity: 178/325 - (54%)
• Gaps: 34/325 - (10%)

  Fly    41 VRLSSGHEMPVLGFGTY------KLRGYQCSAAVHCAIETGFRHFDTAYYYENEKEIGEALRTQI 99
            |:|:.||.:|.|||||.      |.:..:   |||.||:.|:.|.|||..|:.|:|||:|::::|
  Rat     8 VKLNDGHFIPALGFGTSIPNEVPKSKSLE---AVHLAIDAGYHHIDTASAYQIEEEIGQAIQSKI 69

  Fly   100 KMGNISRENIFLTTKLWNTHHDPRDVRRICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMS 164
            |.|.:.||::|:|||||.|...|..|:...||.|:.|...|.|||:||:||..|          |
  Rat    70 KAGVVKREDMFITTKLWCTCFRPELVKPALEKSLKNLQLDYADLYIMHYPVPMK----------S 124

  Fly   165 GDELQTVE---------IDYLDTWRAMENLVKLGMVRSIGLSNFNMEQIQRIIQCS--SSKPVVN 218
            ||:...|:         :|:.|||..:|.....|:|:|||:||||.:|::|::...  ..|||.|
  Rat   125 GDKYLPVDDKGKWLLDTVDFCDTWEMLEKCKDAGLVKSIGVSNFNHKQLERLLNKPGLKYKPVCN 189

  Fly   219 QVEIWPGFLQKDLVDYCRYNGIIVTAFSPLGQPNRK----NHCPVYFFSEGMKRLVKKYKRSASQ 279
            |||......|..|:|||:...|::.|:..||....|    .:.||......:..:.||.|||.:.
  Rat   190 QVECHLYMNQSKLLDYCKSKDIVLVAYGALGTQRYKEWVDQNSPVLLDDPVLCDVAKKNKRSPAL 254

  Fly   280 IVLRYLIDYGVVPIPKAANPIHIKENLNIFDFKLDEADTRLLRGIKPKSRIVKYEIVKDHMFYPF 344
            |.||||:...|||:.::.....::|||.:|:|:|...|.:.|.|:....|.:..|.:..|..|||
  Rat   255 IALRYLVQREVVPLAQSFKENEMRENLQVFEFQLSPEDMKTLDGLNKNFRYLSAEFLAGHPEYPF 319

  Fly   345  344
              Rat   320  319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ARY	NP_001163844.1	AKR_AKR2E1-5	39..331	CDD:381342	116/310 (37%)
Akr1c12l1	NP_001129216.1	AKR_AKR1C1-35	6..308	CDD:381334	116/312 (37%)