Protein Alignment ARY and akr1b1.1

DIOPT Version :10

• Sequence 1: NP_001163844.1
• Gene: ARY / 19988923
• FlyBaseID: FBgn0058064
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_001002048.1
• Gene: akr1b1.1 / 415138
• ZFINID: ZDB-GENE-040625-7
• Length: 315
• Species: Danio rerio
• Alignment Length: 309
• Identity: 119/309 - (38%)
• Similarity: 178/309 - (57%)
• Gaps: 8/309 - (2%)

  Fly    41 VRLSSGHEMPVLGFGTYKLRGYQCSAAVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMGNIS 105
            |.|::|.:||::|.||::....:.:.||..||.:|:||.|.|:.||||.|:|:.:...|..|.:.
Zfish     4 VTLNNGAKMPIVGLGTWRSPPGEVTEAVKSAILSGYRHIDGAHVYENENEVGDGICAMINQGVVK 68

  Fly   106 RENIFLTTKLWNTHHDPRDVRRICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMSGD-ELQ 169
            ||::|:.:|||.|.|:...||..|||.|..|...|:||||||||:|.|...|  |.|:..| .:.
Zfish    69 REDLFIVSKLWCTFHEKHLVRGACEKTLSDLKLDYVDLYLMHFPMGTKPGKD--LFPLDKDGHVI 131

  Fly   170 TVEIDYLDTWRAMENLVKLGMVRSIGLSNFNMEQIQRIIQCS--SSKPVVNQVEIWPGFLQKDLV 232
            ....::|:||.|||.||..|:|::||:||||.:||:.|:...  ..||..||:|..|...|:.|:
Zfish   132 PDNSNFLETWEAMEELVDAGLVKAIGISNFNRDQIEAILNKPGLKYKPANNQIECHPYLTQEKLI 196

  Fly   233 DYCRYNGIIVTAFSPLGQPNR---KNHCPVYFFSEGMKRLVKKYKRSASQIVLRYLIDYGVVPIP 294
            :||:..||.|||:||||.|||   :...|.......:|.:..|:.::.:|:::.:.|...||.||
Zfish   197 NYCQSKGITVTAYSPLGSPNRPWAQADEPSLLEDPKIKAIADKHGKTTAQVLIHFHIQRNVVVIP 261

  Fly   295 KAANPIHIKENLNIFDFKLDEADTRLLRGIKPKSRIVKYEIVKDHMFYP 343
            |:..|..||||..:|||:|.:.:...:.......|....|....|..:|
Zfish   262 KSVTPSRIKENFEVFDFELSKEEMNTILSFNRNFRAFGLEWASKHKDFP 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ARY	NP_001163844.1	AKR_AKR2E1-5	39..331	CDD:381342	116/295 (39%)
akr1b1.1	NP_001002048.1	AKR_AKR1B1-19	9..315	CDD:381333	117/304 (38%)