Protein Alignment ARY and GCLM

DIOPT Version :10

• Sequence 1: NP_001163844.1
• Gene: ARY / 19988923
• FlyBaseID: FBgn0058064
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: XP_047273987.1
• Gene: GCLM / 2730
• HGNCID: 4312
• Length: 275
• Species: Homo sapiens
• Alignment Length: 202
• Identity: 44/202 - (21%)
• Similarity: 90/202 - (44%)
• Gaps: 32/202 - (15%)

  Fly    33 KALL-MAPKVRLSSGHEMPVLGFGTYKLRGYQC----SAAVHCAIETGFRHFDTAYYYENEKEIG 92
            |||| .|..:.|.:|:   :|.:|  :|| .:|    |..:|..|:.....:.:....:..:|..
Human     9 KALLARARTLHLQTGN---LLNWG--RLR-KKCPSTHSEELHDCIQKTLNEWSSQINPDLVREFP 67

  Fly    93 EALRTQI-----KMGNISRENIFLTTKLWNTH-HDPRDVRRICEKQLELLGFSYIDLYLMHFPVG 151
            :.|...:     |:....||.:.::.||:... :.....|...:....:||.:.:|..::..|
Human    68 DVLECTVSHAVEKINPDEREEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVIIASP-- 130

  Fly   152 YKYVCDEILMPMSGDELQTVEIDYLDT-WRAMENLVKLGMVRSIGLSNFNMEQIQRIIQCSSSKP 215
                      |:  ::...:.:::|.. |..:||||:...:.:||.|:.:..|::::.|.:..||
Human   131 ----------PI--EDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKP 183

  Fly   216 VVNQVEI 222
            ..|||.:
Human   184 NSNQVNL 190

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ARY	NP_001163844.1	AKR_AKR2E1-5	39..331	CDD:381342	39/195 (20%)
GCLM	XP_047273987.1	AKR_SF	<86..>211	CDD:444925	26/119 (22%)