Protein Alignment ARY and AKR1C1

DIOPT Version :9

• Sequence 1: NP_001163844.1
• Gene: ARY / 19988923
• FlyBaseID: FBgn0058064
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_001344.2
• Gene: AKR1C1 / 1645
• HGNCID: 384
• Length: 323
• Species: Homo sapiens
• Alignment Length: 313
• Identity: 118/313 - (37%)
• Similarity: 180/313 - (57%)
• Gaps: 10/313 - (3%)

  Fly    41 VRLSSGHEMPVLGFGTY---KLRGYQCSAAVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMG 102
            |:|:.||.|||||||||   ::...:...|...|||.||||.|:|:.|.||:::|.|:|::|..|
Human     8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADG 72

  Fly   103 NISRENIFLTTKLWNTHHDPRDVRRICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMSGDE 167
            ::.||:||.|:|||...|.|..||...|:.|:.|...|:||||:||||..| ..:|::......:
Human    73 SVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK-PGEEVIPKDENGK 136

  Fly   168 LQTVEIDYLDTWRAMENLVKLGMVRSIGLSNFNMEQIQRIIQCS--SSKPVVNQVEIWPGFLQKD 230
            :....:|...||.|:|.....|:.:|||:||||..|::.|:...  ..|||.||||..|.|.|:.
Human   137 ILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRK 201

  Fly   231 LVDYCRYNGIIVTAFSPLG----QPNRKNHCPVYFFSEGMKRLVKKYKRSASQIVLRYLIDYGVV 291
            |:|:|:...|::.|:|.||    :|....:.||......:..|.||:||:.:.|.|||.:..|||
Human   202 LLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVV 266

  Fly   292 PIPKAANPIHIKENLNIFDFKLDEADTRLLRGIKPKSRIVKYEIVKDHMFYPF 344
            .:.|:.|...|::|:.:|:|:|...:.:.:.|:....|.:..:|......|||
Human   267 VLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPF 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ARY	NP_001163844.1	ARA1	37..332	CDD:223729	114/299 (38%)
		Tas	50..324	CDD:223739	107/282 (38%)
AKR1C1	NP_001344.2	AKR_AKR1C1-35	6..308	CDD:381334	114/300 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.730