Protein Alignment ARY and Akr1b8

DIOPT Version :10

• Sequence 1: NP_001163844.1
• Gene: ARY / 19988923
• FlyBaseID: FBgn0058064
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_032038.1
• Gene: Akr1b8 / 14187
• MGIID: 107673
• Length: 316
• Species: Mus musculus
• Alignment Length: 295
• Identity: 114/295 - (38%)
• Similarity: 172/295 - (58%)
• Gaps: 24/295 - (8%)

  Fly    37 MAPKVRLSSGHEMPVLGFGTYKLRGYQCSAAVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKM 101
            ||..|.||:..:||::|.||:|....|...||..||:.|:||.|.||.|.||.|:|||::.:||.
Mouse     1 MATFVELSTKAKMPIVGLGTWKSPPNQVKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQEKIKE 65

  Fly   102 GNISRENIFLTTKLWNTHHDPRDVRRICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMSGD 166
            ..:.||::|:.:|||.|..:.:.::...:|.|..|...|:||||:|:|.|        |.|  |.
Mouse    66 KAVQREDLFIVSKLWPTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQG--------LQP--GK 120

  Fly   167 EL---------QTVEIDYLDTWRAMENLVKLGMVRSIGLSNFNMEQIQRIIQCS--SSKPVVNQV 220
            ||         .|.:..:|:.|..||.||..|:|:::|:||||..||:|::...  ..|||.|||
Mouse   121 ELFPKDDQGRILTSKTTFLEAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQV 185

  Fly   221 EIWPGFLQKDLVDYCRYNGIIVTAFSPLGQPNR---KNHCPVYFFSEGMKRLVKKYKRSASQIVL 282
            |..|...|:.|:.||...||.|||:||||.|:|   |...|.......:|.:..|::::::|:::
Mouse   186 ECHPYLTQEKLIQYCHSKGISVTAYSPLGSPDRPSAKPEDPSLLEDPKIKEIAAKHEKTSAQVLI 250

  Fly   283 RYLIDYGVVPIPKAANPIHIKENLNIFDFKLDEAD 317
            |:.|...||.|||:..|..|:||:.:|||:|.:.:
Mouse   251 RFHIQRNVVVIPKSVTPSRIQENIQVFDFQLSDEE 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ARY	NP_001163844.1	AKR_AKR2E1-5	39..331	CDD:381342	112/293 (38%)
Akr1b8	NP_032038.1	AKR_AKR1B1-19	10..316	CDD:381333	109/286 (38%)