Protein Alignment ARY and Akr1c20

DIOPT Version :10

• Sequence 1: NP_001163844.1
• Gene: ARY / 19988923
• FlyBaseID: FBgn0058064
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_001298061.1
• Gene: Akr1c20 / 116852
• MGIID: 2151104
• Length: 323
• Species: Mus musculus
• Alignment Length: 318
• Identity: 120/318 - (37%)
• Similarity: 176/318 - (55%)
• Gaps: 20/318 - (6%)

  Fly    41 VRLSSGHEMPVLGFGT---YKLRGYQCSAAVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMG 102
            |.|:.||.:|:|||||   .::...:.:.|...||:.||||.|.|..|:||||:|.|:|::|..|
Mouse     8 VLLNDGHFIPILGFGTSAPQEVPRSKATEATKIAIDAGFRHIDCAAVYQNEKEVGLAIRSKIVDG 72

  Fly   103 NISRENIFLTTKLWNTHHDPRDVRRICEKQLELLGFSYIDLYLMHFPVGYK-----YVCDEILMP 162
            .:.||:||.|:|:|.|.|.|..|:...|:.|:.|...|:||||:|||:..|     :..||
Mouse    73 TVKREDIFCTSKVWQTFHRPELVQVCLEQSLKQLQLDYVDLYLIHFPIAMKPGENYFPKDE---- 133

  Fly   163 MSGDELQTVEIDYLDTWRAMENLVKLGMVRSIGLSNFNMEQIQRIIQCS--SSKPVVNQVEIWPG 225
             :|..:... :|..|||.|||.....|:.:|||:.|||..|:::|:...  ..|||.||||..|.
Mouse   134 -NGKFIYDA-VDICDTWEAMEKCKDAGLAKSIGVCNFNRRQLEKILSKPGLKYKPVCNQVECHPY 196

  Fly   226 FLQKDLVDYCRYNGIIVTAFSPLGQPNRK----NHCPVYFFSEGMKRLVKKYKRSASQIVLRYLI 286
            ..|:.|:|:||...|::.|.|.||....|    ...||......:..:.|||.|:.:.|.|||.:
Mouse   197 LNQRKLLDFCRSKDIVLVAHSALGSNRDKEWVDKSFPVLLDDPVLGSMAKKYNRTPALIALRYQV 261

  Fly   287 DYGVVPIPKAANPIHIKENLNIFDFKLDEADTRLLRGIKPKSRIVKYEIVKDHMFYPF 344
            ..|||.:.|:.....||||:.:|:|:|...|.::|.|:....|.:...|.:||..:||
Mouse   262 QRGVVVLAKSFIEKRIKENMQVFEFQLTSVDMKVLDGLNKNIRYIGSSISEDHPDFPF 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ARY	NP_001163844.1	AKR_AKR2E1-5	39..331	CDD:381342	115/303 (38%)
Akr1c20	NP_001298061.1	AKR_AKR1C1-35	6..306	CDD:381334	115/303 (38%)