Protein Alignment ARY and Akr1b3

DIOPT Version :9

• Sequence 1: NP_001163844.1
• Gene: ARY / 19988923
• FlyBaseID: FBgn0058064
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_033788.3
• Gene: Akr1b3 / 11677
• MGIID: 1353494
• Length: 316
• Species: Mus musculus
• Alignment Length: 313
• Identity: 124/313 - (39%)
• Similarity: 185/313 - (59%)
• Gaps: 6/313 - (1%)

  Fly    37 MAPKVRLSSGHEMPVLGFGTYKLRGYQCSAAVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKM 101
            ||..:.|::|.:||.||.||:|....|.:.||..||:.|:||.|.|..|:||||:|.||:.::|.
Mouse     1 MASHLELNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVALQEKLKE 65

  Fly   102 GNISRENIFLTTKLWNTHHDPRDVRRICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMSGD 166
            ..:.|:::|:.:|||.|.||...|:...:|.|..|...|:||||:|:|.|:|...|...:..||:
Mouse    66 QVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLDASGN 130

  Fly   167 ELQTVEIDYLDTWRAMENLVKLGMVRSIGLSNFNMEQIQRIIQCS--SSKPVVNQVEIWPGFLQK 229
            .:.: :.|::|||.|||.||..|:|::||:||||..||:||:...  ..||.|||:|..|...|:
Mouse   131 VIPS-DTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQE 194

  Fly   230 DLVDYCRYNGIIVTAFSPLGQPNR---KNHCPVYFFSEGMKRLVKKYKRSASQIVLRYLIDYGVV 291
            .|::||...||:|||:||||.|:|   |...|.......:|.:..||.::.:|:::|:.|...:|
Mouse   195 KLIEYCHSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKYNKTTAQVLIRFPIQRNLV 259

  Fly   292 PIPKAANPIHIKENLNIFDFKLDEADTRLLRGIKPKSRIVKYEIVKDHMFYPF 344
            .|||:..|:.|.|||.:|||::...|...|.......|:........|..|||
Mouse   260 VIPKSVTPVRIAENLKVFDFEVSSEDMATLLSYNRNWRVCALMSCAKHKDYPF 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ARY	NP_001163844.1	ARA1	37..332	CDD:223729	120/299 (40%)
		Tas	50..324	CDD:223739	114/278 (41%)
Akr1b3	NP_033788.3	ARA1	1..297	CDD:223729	119/296 (40%)
		Tas	8..289	CDD:223739	115/281 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.730