Protein Alignment ARY and AKR1C4

DIOPT Version :9

• Sequence 1: NP_001163844.1
• Gene: ARY / 19988923
• FlyBaseID: FBgn0058064
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_001809.4
• Gene: AKR1C4 / 1109
• HGNCID: 387
• Length: 323
• Species: Homo sapiens
• Alignment Length: 323
• Identity: 128/323 - (39%)
• Similarity: 179/323 - (55%)
• Gaps: 19/323 - (5%)

  Fly    37 MAPK---VRLSSGHEMPVLGFGTYKLRGYQCSAAVH---CAIETGFRHFDTAYYYENEKEIGEAL 95
            |.||   |.|:.||.|||||||||.......:.||.   .|||.||||.|:||.|.||:::|.|:
Human     1 MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAI 65

  Fly    96 RTQIKMGNISRENIFLTTKLWNTHHDPRDVRRICEKQLELLGFSYIDLYLMHFPVGYKYVCDEIL 160
            |::|..|::.||:||.|:|||.|...|:.|:...|..|:.|...|:||||:|||:..|    ...
Human    66 RSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALK----PGE 126

  Fly   161 MPMSGDELQTVEIDYLD---TWRAMENLVKLGMVRSIGLSNFNMEQIQRIIQCS--SSKPVVNQV 220
            .|:..||...|..|.:|   ||..||.....|:.:|||:||||..|::.|:...  ..|||.|||
Human   127 TPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQV 191

  Fly   221 EIWPGFLQKDLVDYCRYNGIIVTAFSPLGQPNRK----NHCPVYFFSEGMKRLVKKYKRSASQIV 281
            |..|...|..|:|:|:...|::.|.|.||....|    .:.||......:..|.||:|::.:.|.
Human   192 ECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKQTPALIA 256

  Fly   282 LRYLIDYGVVPIPKAANPIHIKENLNIFDFKLDEADTRLLRGIKPKSRIVKYEIVKDHMFYPF 344
            |||.:..|||.:.|:.|...|:||:.:|:|:|...|.::|.|:....|.|..:.:.||..|||
Human   257 LRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDFLMDHPDYPF 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ARY	NP_001163844.1	ARA1	37..332	CDD:223729	122/309 (39%)
		Tas	50..324	CDD:223739	112/285 (39%)
AKR1C4	NP_001809.4	AKR_AKR1C1-35	6..306	CDD:381334	119/303 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.830