Protein Alignment ARY and AKR1A1

DIOPT Version :9

• Sequence 1: NP_001163844.1
• Gene: ARY / 19988923
• FlyBaseID: FBgn0058064
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_001189342.1
• Gene: AKR1A1 / 10327
• HGNCID: 380
• Length: 325
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 124/325 - (38%)
• Similarity: 177/325 - (54%)
• Gaps: 20/325 - (6%)

  Fly    36 LMAPKVRLSSGHEMPVLGFGTYKLRGYQCSAAVHCAIETGFRHFDTAYYYENEKEIGEALRTQIK 100
            :.|..|.|.:|.:||::|.||:|....|..|||..|:..|:||.|.|..|.||.||||||:..:.
Human     1 MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65

  Fly   101 MGN-ISRENIFLTTKLWNTHHDPRDVRRICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMS 164
            .|. :.||.:|:|:|||||.|.|.||.....|.|..|...|:||||||:|  |.:...:...|.:
Human    66 PGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWP--YAFERGDNPFPKN 128

  Fly   165 GDELQTVEID---YLDTWRAMENLVKLGMVRSIGLSNFNMEQIQRIIQCSSSKPVVNQVEIWPGF 226
            .|  .|:..|   |.:||:|:|.||..|:|:::||||||..||..|:..:|.:|.|.|||..|..
Human   129 AD--GTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYL 191

  Fly   227 LQKDLVDYCRYNGIIVTAFSPLGQPN---RKNHCPVYFFSEGMKRLVKKYKRSASQIVLRYLIDY 288
            .|.:|:.:|:..|:.|||:||||..:   |....||......:..|.:||.||.:||:||:.:..
Human   192 AQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQR 256

  Fly   289 GVVPIPKAANPIHIKENLNIFDFKLDEADTRLLRGIKPKSRIVKYEIVKD---------HMFYPF 344
            .|:.|||:..|..|.:|:.:|||.....:.:.|..:....|.:...:..|         |..|||
Human   257 KVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRVPRDAGHPLYPF 321

  Fly   345  344
            Human   322  321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ARY	NP_001163844.1	ARA1	37..332	CDD:223729	119/301 (40%)
		Tas	50..324	CDD:223739	113/280 (40%)
AKR1A1	NP_001189342.1	ARA1	6..303	CDD:223729	118/300 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.690