DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpl6 and RpL6

DIOPT Version :9

Sequence 1:	NP_035420.2	Gene:	Rpl6 / 19988	MGIID:	108057	Length:	296	Species:	Mus musculus
Sequence 2:	NP_651876.1	Gene:	RpL6 / 43723	FlyBaseID:	FBgn0039857	Length:	262	Species:	Drosophila melanogaster

Alignment Length:	270	Identity:	127/270 - (47%)
Similarity:	166/270 - (61%)	Gaps:	21/270 - (7%)

- Green bases have known domain annotations that are detailed below.

Mouse    34 AKKVHPKGKKPKKAKPHCSRNPVLVRGIGRYSRSAMYSRKALYKRKYSAAKTKVEKKK---KKEK 95
            ||||   .|..||.|.| ..|..|..||.|||::.||.|:|||:.|        :||.   :|.|
  Fly     7 AKKV---AKSAKKGKKH-PVNSYLKGGILRYSKAQMYKRRALYRLK--------DKKSPVVEKAK 59

Mouse    96 VLATVTKTVGGDKNGGTRVVKLRKMPRYYPTEDVPRKLLSHGKKPFSQHVRRLRSSITPGTVLII 160
            |.....|.:||.||||.|.|.|:|....|||:...:|..|  |..||:|.|..|.::|||||||:
  Fly    60 VPIKKVKKIGGPKNGGERTVFLKKSKASYPTKTFVKKRPS--KANFSEHKRNTRRNLTPGTVLIL 122

Mouse   161 LTGRHRGKRVVFLKQLDSGLLLVTGPLVINRVPLRRTHQKFVIATSTKVDISDVKIPKHLTDAYF 225
            |.|||:|||||.||.|.|||||||||..:|..||||..|::||.||:|||:...|:|:||.||||
  Fly   123 LAGRHQGKRVVLLKVLASGLLLVTGPFALNSCPLRRVSQRYVIGTSSKVDLGAFKVPEHLNDAYF 187

Mouse   226 KKKQLRKPRHQ-EGEIFDTEKEKYEITEQRKADQKAVDLQILPKIKAVPQ---LQGYLRSQFSLT 286
            ::.:.:|.:.. |.:||..:||::...||||.|||.||..:|..|||.|:   ...||::.|:|.
  Fly   188 RRLKAKKDKKTGEADIFAAKKERFVPNEQRKKDQKEVDAALLKVIKAHPEGKFFAKYLQNMFALH 252

Mouse   287 NGMYPHKLVF 296
            :..|||::.|
  Fly   253 SSQYPHRMRF 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpl6	NP_035420.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..53		9/18 (50%)
		Ribosomal_L6e_N	50..103	CDD:367701	20/55 (36%)
		KOW_RPL6	144..296	CDD:240520	79/155 (51%)
RpL6	NP_651876.1	Ribosomal_L6e_N	<23..>51	CDD:281813	14/35 (40%)
		KOW_RPL6	106..262	CDD:240520	79/155 (51%)
		RPL14A	111..234	CDD:225074	67/122 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830619
Domainoid	1	1.000	97	1.000	Domainoid score	I7289
eggNOG	1	0.900	-	-		E1_COG2163
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H31001
Inparanoid	1	1.050	212	1.000	Inparanoid score	I3633
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53785
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001826
OrthoInspector	1	1.000	-	-		oto94654
orthoMCL	1	0.900	-	-		OOG6_101188
Panther	1	1.100	-	-	LDO	PTHR10715
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1143
SonicParanoid	1	1.000	-	-		X1520
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.790