DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ELF1 and Ets65A

DIOPT Version :9

Sequence 1:	NP_001357259.1	Gene:	ELF1 / 1997	HGNCID:	3316	Length:	619	Species:	Homo sapiens
Sequence 2:	NP_001303373.1	Gene:	Ets65A / 38700	FlyBaseID:	FBgn0005658	Length:	728	Species:	Drosophila melanogaster

Alignment Length:	205	Identity:	66/205 - (32%)
Similarity:	85/205 - (41%)	Gaps:	58/205 - (28%)

- Green bases have known domain annotations that are detailed below.

Human   203 GKGNTIYLWEFLLALLQD--KATCPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMG 265
            |.|. |.||:|||.||.|  .|:|   |.| :...|.|||.|...|:|.||:.|:||:|||:.:.
  Fly   313 GSGQ-IQLWQFLLELLSDSNNASC---ITW-EGTNGEFKLTDPDEVARRWGERKSKPNMNYDKLS 372

Human   266 RALRYYYQRGILAKVEGQRLVYQF---------KEMPKDLIYINDED-----------------P 304
            |||||||.:.|:.||.|:|..|:|         :....|..|....|                 |
  Fly   373 RALRYYYDKNIMTKVHGKRYAYKFDFQGLAAATQPAASDPTYKYQSDLFMTPYHHSAKLSSFMSP 437

Human   305 SSSIESSDPSLSSSATSNRNQTSRSRVSSSPGVKGGATTVLKPGNSKAAKPKDPVEVAQPSEVLR 369
            ...:.||..|:..||.|..|.       .||     ||.:.:|.:.....|..
  Fly   438 HHGMTSSSASIFPSAASWGNW-------GSP-----ATNLYQPHSMSHVTPSH------------ 478

Human   370 TVQPTQSPYP 379
             |.|..|.||
  Fly   479 -VAPHLSSYP 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ELF1	NP_001357259.1	Elf-1_N	2..111	CDD:372034
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	158..199
		ETS	207..289	CDD:197710	41/83 (49%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	300..366		15/82 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	564..592
Ets65A	NP_001303373.1	ETS	316..401	CDD:197710	42/89 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910