DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ELAVL4 and CG6937

DIOPT Version :9

Sequence 1:	XP_011539191.1	Gene:	ELAVL4 / 1996	HGNCID:	3315	Length:	416	Species:	Homo sapiens
Sequence 2:	NP_651066.2	Gene:	CG6937 / 42662	FlyBaseID:	FBgn0038989	Length:	356	Species:	Drosophila melanogaster

Alignment Length:	177	Identity:	45/177 - (25%)
Similarity:	79/177 - (44%)	Gaps:	10/177 - (5%)

- Green bases have known domain annotations that are detailed below.

Human    84 LIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRL 148
            :||.:||....:::.|..|...|.:...:|.|...||.|.||.||.:..|:.|:.|.:|::...:
  Fly    53 VIVKHLPHGFFEQQLRQYFRQFGRVLRVRLARSLRTGNSKGYAFVEFEYPEVAKVAADTMDNYLM 117

Human   149 QTKTIKVSYARPSSASIRDANLYVSGLPKTMTQ--KEL--EQLFSQYGRIITSRILVDQVTGVSR 209
            ..|.:|.:|..|...::   |.:.:.|.|.:.:  ||:  ..|.....|.:..:...|:.....|
  Fly   118 FQKVVKATYIPPEKQTL---NFFRTSLKKVVNKAGKEIYVSDLTKATQRSVKKQNNWDESACQKR 179

Human   210 GVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQA 256
            .|..:...|::  :|..|.|.....:...||:. |.|.:....:|||
  Fly   180 TVANLNKIKKL--QEKYKDLGIDFSNLLVEPVK-KAAGSAEASTSQA 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ELAVL4	XP_011539191.1	ELAV_HUD_SF	79..415	CDD:273741	45/177 (25%)
CG6937	NP_651066.2	RRM	<32..>170	CDD:223796	31/119 (26%)
		RRM_NIFK_like	52..125	CDD:240753	22/71 (31%)
		Upf2	253..>304	CDD:281974
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910