DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ELAVL4 and nonA-l

DIOPT Version :9

Sequence 1:	XP_011539191.1	Gene:	ELAVL4 / 1996	HGNCID:	3315	Length:	416	Species:	Homo sapiens
Sequence 2:	NP_001262646.1	Gene:	nonA-l / 42026	FlyBaseID:	FBgn0015520	Length:	630	Species:	Drosophila melanogaster

Alignment Length:	226	Identity:	53/226 - (23%)
Similarity:	89/226 - (39%)	Gaps:	34/226 - (15%)

- Green bases have known domain annotations that are detailed below.

Human    77 TDD---SKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEK 138
            ||:   .:..|.|..|..:.|.::.|.:|...|||      .|..:.....:.|:.....::|||
  Fly   257 TDNKFVGRNRLYVGNLTSDTTDDDLREMFKPYGEI------GDIFSNPEKNFTFLRLDYYQNAEK 315

Human   139 AINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQ 203
            |...|:|...:.:.::|.:|..:...:.:.|.:||       .:.|.|.|..:|.|..:.|.||.
  Fly   316 AKRALDGSLRKGRVLRVRFAPNAIVRVTNLNQFVS-------NELLHQSFEIFGPIERAVICVDD 373

Human   204 VTGVSRGVGFIRFDKRIEAEEAIKGLNGQ--------KPSGATEPITVKFANNPSQKSSQALLSQ 260
             .|...|.|.:.|.|:..|...::..|.:        :|. ..||:.|.  |:......:.|..:
  Fly   374 -RGKHTGEGIVEFAKKSSASACLRLCNEKCFFLTASLRPC-LVEPMEVN--NDNDGLPDKTLNKK 434

Human   261 LYQSPNRRYPGPLHHQAQRFRLDNLLNMAYG 291
            ..:..:.|..||      ||...|.....||
  Fly   435 SLEFRHERSVGP------RFACLNSFEHEYG 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ELAVL4	XP_011539191.1	ELAV_HUD_SF	79..415	CDD:273741	51/224 (23%)
nonA-l	NP_001262646.1	RRM1_p54nrb_like	264..334	CDD:240778	18/75 (24%)
		RRM2_p54nrb_like	339..418	CDD:240779	21/87 (24%)
		NOPS_NONA_like	409..508	CDD:240580	14/60 (23%)
		OmpH	<479..578	CDD:281871
		DUF4472	479..559	CDD:291409
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910