DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ELAVL4 and mug28

DIOPT Version :9

Sequence 1:	XP_011539191.1	Gene:	ELAVL4 / 1996	HGNCID:	3315	Length:	416	Species:	Homo sapiens
Sequence 2:	NP_593427.1	Gene:	mug28 / 2543165	PomBaseID:	SPAC343.07	Length:	609	Species:	Schizosaccharomyces pombe

Alignment Length:	254	Identity:	64/254 - (25%)
Similarity:	94/254 - (37%)	Gaps:	66/254 - (25%)

- Green bases have known domain annotations that are detailed below.

Human    69 SPMQTGATTDDSKTNLIVNYLPQNM--TQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYI 131
            :|..|...|.| ..||.|..|..|:  ..::...||...|.|:||.|.....|..|.|||||::.
pombe   407 TPTPTSTPTID-PCNLFVKNLDDNIVGNTQQLEELFSKFGRIKSCTLASYPSTEISKGYGFVSFS 470

Human   132 DPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQ-YGRII 195
            .|.:|.:|||||||:....|.:.|:||.                .:...:|.|..:||| |..::
pombe   471 HPFEAVQAINTLNGVLFGKKRLFVNYAE----------------KREDRKKRLSAIFSQSYPPVV 519

Human   196 TSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQ 260
            .|..|...:                                ||||..:::.....|...|::...
pombe   520 PSPSLTIPM--------------------------------ATEPQILEYHQEWPQPLIQSIQQH 552

Human   261 LYQSPNRRYPGPLHHQAQRFR----LDNLLNMA--YGVKRLMSGPVPPSACPPRFSPIT 313
            .|..|.:..|..|...|.:.|    .:..||.:  :|:|.        |......||:|
pombe   553 GYSDPRQTLPTRLDSCAAKLREAVISNENLNPSHKFGIKH--------STFKTSLSPLT 603

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ELAVL4	XP_011539191.1	ELAV_HUD_SF	79..415	CDD:273741	61/244 (25%)
mug28	NP_593427.1	RRM	<8..>127	CDD:223796
		RRM1_NEFsp	21..100	CDD:240719
		RRM	150..505	CDD:223796	36/114 (32%)
		RRM_SF	274..342	CDD:240668
		RRM_SF	417..496	CDD:302621	31/79 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10352
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010