Protein Alignment ELAVL3 and shep

DIOPT Version :10

• Sequence 1: NP_001411.2
• Gene: ELAVL3 / 1995
• HGNCID: 3314
• Length: 367
• Species: Homo sapiens
• Sequence 2: NP_001246636.1
• Gene: shep / 38605
• FlyBaseID: FBgn0052423
• Length: 590
• Species: Drosophila melanogaster
• Alignment Length: 280
• Identity: 81/280 - (28%)
• Similarity: 130/280 - (46%)
• Gaps: 52/280 - (18%)

Human    23 PNGPLLGTN--GATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFV 85
            |||.:...|  |....|||||.:..|.|..|..:..::....|.|.|.|.:.||.|.:..|||||
  Fly   225 PNGTVQNQNQQGGEQLSKTNLYIRGLQQGTTDKDLVNMCAQYGTIISTKAILDKTTNKCKGYGFV 289

Human    86 NYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGR 150
            ::..|..|:.|:..|.|..:|.:..|.....|:       |||::.||....:.::|.:.|:||:
  Fly   290 DFEQPAFAECAVKGLQGKGVQAQMAKQQEQDPT-------NLYIANLPPHFKETDLEAMLSKYGQ 347

Human   151 IITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFAN-NPSQKTGQAL 214
            ::::|||.||... |:||||.|.:.|.:.|:.|:..||....||.:|:.||||: .|.:|
  Fly   348 VVSTRILRDQQMN-SKGVGFARMESREKCEQIIQMFNGNTIPGAKDPLLVKFADGGPKKK----- 406

Human   215 LTHLYQS---SARRYA-----------GPLHHQTQRFRLDNLLNMAYGVKSPLSL-IARFSPIAI 264
              :|:::   :||.:.           .|...|.         .::..|.:|:.: .:|||...:
  Fly   407 --NLFKTPDPNARAWRDVSAEGIPVAYDPTMQQN---------GVSVNVGTPIGVPYSRFSAPQV 460

Human   265 DGMSGLAGVGLSGGAAGAGW 284
            .|..          .||:.|
  Fly   461 GGYP----------VAGSQW 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ELAVL3	NP_001411.2	ELAV_HUD_SF	36..366	CDD:273741	76/265 (29%)
shep	NP_001246636.1	RRM_SF	240..321	CDD:473069	27/80 (34%)
		RRM2_MSSP	322..400	CDD:409690	31/85 (36%)