Protein Alignment ELAVL1 and shep

DIOPT Version :10

• Sequence 1: XP_047294339.1
• Gene: ELAVL1 / 1994
• HGNCID: 3312
• Length: 353
• Species: Homo sapiens
• Sequence 2: NP_001246636.1
• Gene: shep / 38605
• FlyBaseID: FBgn0052423
• Length: 590
• Species: Drosophila melanogaster
• Alignment Length: 294
• Identity: 89/294 - (30%)
• Similarity: 137/294 - (46%)
• Gaps: 50/294 - (17%)

Human     3 SGGRSAQVSTGQRAWLLPCRFLKNTMS-------NGYEDHMAEDCRGDIGRTNLIVNYLPQNMTQ 60
            :|.:|..:||.          |.||.:       ||...:..:.....:.:|||.:..|.|..|.
  Fly   202 TGSQSGTLSTS----------LSNTTNTNTNMGPNGTVQNQNQQGGEQLSKTNLYIRGLQQGTTD 256

Human    61 DELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVSYARP 125
            .:|.::.:..|.:.|.|.|.||......|||||::.....||.|:..|.|..:|::..|.....|
  Fly   257 KDLVNMCAQYGTIISTKAILDKTTNKCKGYGFVDFEQPAFAECAVKGLQGKGVQAQMAKQQEQDP 321

Human   126 SSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEA 190
            :       ||||:.||....:.|:|.|.|::|:::::|:|.||... |:||.|.|.:.|.:.|:.
  Fly   322 T-------NLYIANLPPHFKETDLEAMLSKYGQVVSTRILRDQQMN-SKGVGFARMESREKCEQI 378

Human   191 ITSFNGHKPPGSSEPITVKFAANPNQNKNVALLSQLYHSP---ARRF------GGPVHHQ--AQR 244
            |..|||:..||:.:|:.||||....:.||      |:.:|   ||.:      |.||.:.  .|:
  Fly   379 IQMFNGNTIPGAKDPLLVKFADGGPKKKN------LFKTPDPNARAWRDVSAEGIPVAYDPTMQQ 437

Human   245 FRFS-----PMGVDHMSGLSGVNVPGN--ASSGW 271
            ...|     |:||.: |..|...|.|.  |.|.|
  Fly   438 NGVSVNVGTPIGVPY-SRFSAPQVGGYPVAGSQW 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ELAVL1	XP_047294339.1	ELAV_HUD_SF	46..353	CDD:273741	80/244 (33%)
shep	NP_001246636.1	RRM_SF	240..321	CDD:473069	25/80 (31%)
		RRM2_MSSP	322..400	CDD:409690	32/85 (38%)