Protein Alignment ELAVL1 and Sxl

DIOPT Version :10

• Sequence 1: XP_047294339.1
• Gene: ELAVL1 / 1994
• HGNCID: 3312
• Length: 353
• Species: Homo sapiens
• Sequence 2: NP_001259303.1
• Gene: Sxl / 3772180
• FlyBaseID: FBgn0264270
• Length: 722
• Species: Drosophila melanogaster
• Alignment Length: 240
• Identity: 100/240 - (41%)
• Similarity: 147/240 - (61%)
• Gaps: 12/240 - (5%)

Human     2 GSGGR--SAQVSTGQRAWLLPCRFLKNTMSN--------GYEDHMAEDCRGDIGRTNLIVNYLPQ 56
            ||||.  ||....|.....||.....|:::|        |..|.:..|.|.  ..||||||||||
  Fly    64 GSGGNGGSANNLGGGNMCHLPPMASNNSLNNLCGLSLGSGGSDDLMNDPRA--SNTNLIVNYLPQ 126

Human    57 NMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVS 121
            :||..||.:||.:||.:.:.:::||...|:|.||.||::.:..|::|||..|||:.:::|.:|||
  Fly   127 DMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQRAIKVLNGITVRNKRLKVS 191

Human   122 YARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSE 186
            ||||..|.|||.|||::.||||:|...::.:|.::|.|:...:|.|:.||..|||||:|::||.|
  Fly   192 YARPGGESIKDTNLYVTNLPRTITDDQLDTIFGKYGSIVQKNILRDKLTGRPRGVAFVRYNKREE 256

Human   187 AEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLSQLYHSPA 231
            |:|||::.|...|.|.|:|::|:.|....:.|....:||:...||
  Fly   257 AQEAISALNNVIPEGGSQPLSVRLAEEHGKAKAAHFMSQMGVVPA 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ELAVL1	XP_047294339.1	ELAV_HUD_SF	46..353	CDD:273741	85/186 (46%)
Sxl	NP_001259303.1	sex-lethal	16..297	CDD:273740	98/234 (42%)