Protein Alignment ELAVL2 and Sxl

DIOPT Version :10

• Sequence 1: XP_047278864.1
• Gene: ELAVL2 / 1993
• HGNCID: 3313
• Length: 411
• Species: Homo sapiens
• Sequence 2: NP_001259303.1
• Gene: Sxl / 3772180
• FlyBaseID: FBgn0264270
• Length: 722
• Species: Drosophila melanogaster
• Alignment Length: 289
• Identity: 108/289 - (37%)
• Similarity: 160/289 - (55%)
• Gaps: 34/289 - (11%)

Human    58 NGPTCNNTANG----------PTTINNNCSSPVDSGNTED-------SKTNLIVNYLPQNMTQEE 105
            ||.:.||...|          ..::||.|...:.||.::|       |.||||||||||:||..|
  Fly    68 NGGSANNLGGGNMCHLPPMASNNSLNNLCGLSLGSGGSDDLMNDPRASNTNLIVNYLPQDMTDRE 132

Human   106 LKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSS 170
            |.:||.:||.|.:|:::||..||.|.||.||::....|:::||..|||:.::.|.:|||||||..
  Fly   133 LYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQRAIKVLNGITVRNKRLKVSYARPGG 197

Human   171 ASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIK 235
            .||:|.||||:.||:|:|..:|:.:|.:||.|:...||.|::||..|||.|:|::||.||:|||.
  Fly   198 ESIKDTNLYVTNLPRTITDDQLDTIFGKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAIS 262

Human   236 GLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPNR---RYPGPLAQQAQRFRL------- 290
            .||...|.|.::|::|:.|....:......:||:...|..   ..|.|.|..|..|.:
  Fly   263 ALNNVIPEGGSQPLSVRLAEEHGKAKAAHFMSQMGVVPANVPPPPPQPPAHMAAAFNMMHRDGAM 327

Human   291 -------DNLLNMAYGVKSRFSPMTIDGM 312
                   |.:.:..:|:.|......:||:
  Fly   328 EKLRSLFDAICDAIFGLDSENFADLLDGL 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ELAVL2	XP_047278864.1	ELAV_HUD_SF	87..410	CDD:273741	98/250 (39%)
Sxl	NP_001259303.1	sex-lethal	16..297	CDD:273740	97/228 (43%)