DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CYTB and BI4

DIOPT Version :9

Sequence 1:	YP_009047277.1	Gene:	CYTB / 19893556	FlyBaseID:	FBgn0013678	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_009316.1	Gene:	BI4 / 854582	SGDID:	S000007273	Length:	638	Species:	Saccharomyces cerevisiae

Alignment Length:	250	Identity:	137/250 - (54%)
Similarity:	187/250 - (74%)	Gaps:	4/250 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 RNSHPLFKIANNALVDLPAPINISSWWNFGSLLGLCLIIQILTGLFLAMHYTADINLAFYSVNHI 70
            |.|:....:.|:.::|.|.|.:|:.|||.||||||||:|||:||:|:||||:::|.|||.||.||
Yeast     4 RKSNVYLSLVNSYIIDSPQPSSINYWWNMGSLLGLCLVIQIVTGIFMAMHYSSNIELAFSSVEHI 68

  Fly    71 CRDVNYGWLLRTLHANGASFFFICIYLHVGRGIYYGSYKFTP---TWLIGVIILFLVMGTAFMGY 132
            .|||:.|::||.||||||||||:.:::|:.:|:|||||: :|   .|.:||||..|.:.|||:||
Yeast    69 MRDVHNGYILRYLHANGASFFFMVMFMHMAKGLYYGSYR-SPRVTLWNVGVIIFILTIATAFLGY 132

  Fly   133 VLPWGQMSFWGATVITNLLSAIPYLGMDLVQWLWGGFAVDNATLTRFFTFHFILPFIVLAMTMIH 197
            ...:||||.|||||||||.||||::|.|:|.||||||:|.|.|:.|||..|:::|||:.||.::|
Yeast   133 CCVYGQMSHWGATVITNLFSAIPFVGNDIVSWLWGGFSVSNPTIQRFFALHYLVPFIIAAMVIMH 197

  Fly   198 LLFLHQTGSNNPIGLNSNIDKIPFHPYFTFKDIVGFIVMIFILISLVLISPNLLG 252
            |:.||..||:||:|:..|:|:||.|.||.|||:|...:.:.||...|..|||.||
Yeast   198 LMALHIHGSSNPLGITGNLDRIPMHSYFIFKDLVTVFLFMLILALFVFYSPNTLG 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CYTB	YP_009047277.1	CYTB	12..367	CDD:214440	134/243 (55%)
BI4	NP_009316.1	Cytochrome_b_N	8..207	CDD:238176	112/199 (56%)
		cytochrome_b_C	208..>255	CDD:294127	21/44 (48%)
		Hop	<363..592	CDD:224291
		LAGLIDADG_1	408..495	CDD:279328
		LAGLIDADG_1	516..608	CDD:279328
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346802
Domainoid	1	1.000	248	1.000	Domainoid score	I350
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46878
orthoMCL	1	0.900	-	-		OOG6_102198
Panther	1	1.100	-	-	O	PTHR19271
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1779
TreeFam	0	0.000	Not matched by this tool.
	7	6.840