DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CYTB and CYTB

DIOPT Version :9

Sequence 1:	YP_009047277.1	Gene:	CYTB / 19893556	FlyBaseID:	FBgn0013678	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_006958.1	Gene:	CYTB / 2565702	-ID:		Length:	370	Species:	Caenorhabditis elegans

Alignment Length:	368	Identity:	163/368 - (44%)
Similarity:	237/368 - (64%)	Gaps:	17/368 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LRNSHPLFKIANNALVDLPAPINISSWWNFGSLLGLCLIIQILTGLFLAMHYTADINLAFYSVNH 69
            ::.::.|....|..||.||:...::..|||||:||:.||.|||||.|||.:||.|..:||.:|.:
Worm     1 MKINNSLLNFVNGMLVTLPSSKTLTLSWNFGSMLGMVLIFQILTGTFLAFYYTPDSLMAFSTVQY 65

  Fly    70 ICRDVNYGWLLRTLHANGASFFFICIYLHVGRGIYYGSYKFTPTWLIGVIILFLVMGTAFMGYVL 134
            |..:||:||:.|..|.||||.|||.:|||:.:|:::.||:....|:.|:.|..|||..|||||||
Worm    66 IMYEVNFGWVFRIFHFNGASLFFIFLYLHIFKGLFFMSYRLKKVWMSGLTIYLLVMMEAFMGYVL 130

  Fly   135 PWGQMSFWGATVITNLLSAIPYLGMDLVQWLWGGFAVDNATLTRFFTFHFILPFIVLAMTMIHLL 199
            .|.|||||.|.|||:|||.||..|..:|.|:|.||.|..|||..||..||:||:.:|.:.:.||:
Worm   131 VWAQMSFWAAVVITSLLSVIPIWGPTIVTWIWSGFGVTGATLKFFFVLHFLLPWAILVIVLGHLI 195

  Fly   200 FLHQTGSNNPIGLNSNIDKIPFHPYFTFKDIVGFIV-MIFILISLVLISPNLLGDPDNFIPANPL 263
            |||.|||.:.:..:.:.||:.|.|.:..||....:: ::||::|  ||.|..|||.:.||.|:|:
Worm   196 FLHSTGSTSSLYCHGDYDKVCFSPEYLGKDAYNIVIWLLFIVLS--LIYPFNLGDAEMFIEADPM 258

  Fly   264 VTPAHIQPEWYFLFAYAILRSIPNKLGGVIALVLSIAILMILPFYN-----LSKFRGIQFYPINQ 323
            ::|.||.|||||||||||||:||||:.|||||::||.........|     |:|        :|:
Worm   259 MSPVHIVPEWYFLFAYAILRAIPNKVLGVIALLMSIVTFYFFALVNNYTSCLTK--------LNK 315

  Fly   324 VMFWSMLVTVILLTWIGARPVEEPYVLIGQILTVVYF-LYYLV 365
            .:.:..:::..:|:|:|...||:|:.::..:.:.:|| |.||:
Worm   316 FLVFMFIISSTILSWLGQCTVEDPFTILSPLFSFIYFGLAYLM 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CYTB	YP_009047277.1	CYTB	12..367	CDD:214440	162/361 (45%)
CYTB	NP_006958.1	Cytochrome_b_N	7..203	CDD:238176	101/195 (52%)
		CYTB	9..363	CDD:177151	162/360 (45%)
		cytochrome_b_C	206..347	CDD:294127	56/146 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	213	1.000	Domainoid score	I1610
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	326	1.000	Inparanoid score	I1460
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60605
OrthoDB	1	1.010	-	-		D1125966at2759
OrthoFinder	1	1.000	-	-		FOG0004155
OrthoInspector	1	1.000	-	-		oto18244
orthoMCL	1	0.900	-	-		OOG6_102198
Panther	1	1.100	-	-	LDO	PTHR19271
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R280
SonicParanoid	1	1.000	-	-		X1779
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.010