DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CYTB and CYTB

DIOPT Version :9

Sequence 1:	YP_009047277.1	Gene:	CYTB / 19893556	FlyBaseID:	FBgn0013678	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_059343.1	Gene:	CYTB / 140512	ZFINID:	ZDB-GENE-011205-17	Length:	380	Species:	Danio rerio

Alignment Length:	361	Identity:	254/361 - (70%)
Similarity:	315/361 - (87%)	Gaps:	0/361 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LRNSHPLFKIANNALVDLPAPINISSWWNFGSLLGLCLIIQILTGLFLAMHYTADINLAFYSVNH 69
            ||.:||:.||||:||||||.|:|||:|||||||||||||.|||||||||||||:||:.||.||.|
Zfish     4 LRKTHPVLKIANDALVDLPTPLNISAWWNFGSLLGLCLITQILTGLFLAMHYTSDISTAFSSVVH 68

  Fly    70 ICRDVNYGWLLRTLHANGASFFFICIYLHVGRGIYYGSYKFTPTWLIGVIILFLVMGTAFMGYVL 134
            ||||||:|||:|::|||||||||||:|:|:.||:|||||.:..||.|||::..|||.|||:||||
Zfish    69 ICRDVNFGWLIRSIHANGASFFFICLYIHIARGLYYGSYLYNETWNIGVVLFLLVMMTAFVGYVL 133

  Fly   135 PWGQMSFWGATVITNLLSAIPYLGMDLVQWLWGGFAVDNATLTRFFTFHFILPFIVLAMTMIHLL 199
            |||||||||||||||||||:||:|..||||:||||:||||||||||.|||:||||::||.::|||
Zfish   134 PWGQMSFWGATVITNLLSAVPYVGDTLVQWIWGGFSVDNATLTRFFAFHFLLPFIIIAMVILHLL 198

  Fly   200 FLHQTGSNNPIGLNSNIDKIPFHPYFTFKDIVGFIVMIFILISLVLISPNLLGDPDNFIPANPLV 264
            |||:||||||:|||.|:|||||||||:.||::||::|:|.|..|.|.||||||||:||.||||||
Zfish   199 FLHETGSNNPLGLNPNMDKIPFHPYFSNKDLLGFVIMLFSLSLLALFSPNLLGDPENFTPANPLV 263

  Fly   265 TPAHIQPEWYFLFAYAILRSIPNKLGGVIALVLSIAILMILPFYNLSKFRGIQFYPINQVMFWSM 329
            ||.||:||||||||||||||||||||||:||:.||.:||::|..:.||.||:.|.|:.|.:||::
Zfish   264 TPPHIKPEWYFLFAYAILRSIPNKLGGVLALLFSILVLMVVPILHTSKQRGMAFRPVTQFLFWTL 328

  Fly   330 LVTVILLTWIGARPVEEPYVLIGQILTVVYFLYYLV 365
            :..:::|||||..|||.||::|||:.:::||..:||
Zfish   329 VADMLVLTWIGGMPVEHPYIIIGQMASILYFSLFLV 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CYTB	YP_009047277.1	CYTB	12..367	CDD:214440	250/354 (71%)
CYTB	NP_059343.1	CYTB	1..380	CDD:177189	254/361 (70%)
		Cytochrome_b_N	9..206	CDD:238176	150/196 (77%)
		cytochrome_b_C	207..354	CDD:238179	95/146 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596849
Domainoid	1	1.000	327	1.000	Domainoid score	I1153
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	576	1.000	Inparanoid score	I1007
OMA	1	1.010	-	-		QHG60605
OrthoDB	1	1.010	-	-		D1125966at2759
OrthoFinder	1	1.000	-	-		FOG0004155
OrthoInspector	1	1.000	-	-		oto41619
orthoMCL	1	0.900	-	-		OOG6_102198
Panther	1	1.100	-	-	LDO	PTHR19271
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R280
SonicParanoid	1	1.000	-	-		X1779
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.940