Protein Alignment ND5 and ND5

DIOPT Version :10

• Sequence 1: YP_009047273.1
• Gene: ND5 / 19893549
• FlyBaseID: FBgn0013684
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: YP_003024036.1
• Gene: ND5 / 4540
• HGNCID: 7461
• Length: 603
• Species: Homo sapiens
• Alignment Length: 577
• Identity: 206/577 - (35%)
• Similarity: 328/577 - (56%)
• Gaps: 29/577 - (5%)

  Fly    11 SMSLSCFLLSL-----YFLLNDMIYFIEWELVSLNSMSIVMTFLFDWMSLLFMSFVLMISSLVIF 70
            |:..|.|::||     :..|:..:....|...:..:..:.::|..|:.|::|:...|.::..::.
Human    38 SIVASTFIISLFPTTMFMCLDQEVIISNWHWATTQTTQLSLSFKLDYFSMMFIPVALFVTWSIME 102

  Fly    71 YSKEYMMNDNHINRFIMLVLMFVLSMMLLIISPNLISILLGWDGLGLVSYCLVIYFQNIKSYNAG 135
            :|..||.:|.:||:|...:|:|:::|::|:.:.||..:.:||:|:|::|:.|:.::......|..
Human   103 FSLWYMNSDPNINQFFKYLLIFLITMLILVTANNLFQLFIGWEGVGIMSFLLISWWYARADANTA 167

  Fly   136 MLTA-LSNRIGDVALLLSIAW-MLNYGSWNYIFYLEIMQNEFEMLMIGSLVMLAAMTKSAQIPFS 198
            .:.| |.|||||:..:|::|| :|:..||:......:..|.....::|  ::|||..||||:...
Human   168 AIQAILYNRIGDIGFILALAWFILHSNSWDPQQMALLNANPSLTPLLG--LLLAAAGKSAQLGLH 230

  Fly   199 SWLPAAMAAPTPVSALVHSSTLVTAGVYLLIRFNIILSTSWLGQ-LMLLLSGLTMFMAGLGANFE 262
            .|||:||..|||||||:||||:|.||::|||||:.:...|.|.| |.|.|..:|...|.:.|..:
Human   231 PWLPSAMEGPTPVSALLHSSTMVVAGIFLLIRFHPLAENSPLIQTLTLCLGAITTLFAAVCALTQ 295

  Fly   263 FDLKKIIALSTLSQLGLMMSILSMGFLKLAMFHLLTHALFKALLFMCAGAIIHNMNNSQDIRLMG 327
            .|:|||:|.||.|||||||..:.:....||..|:.|||.|||:||||:|:||||:||.||||.||
Human   296 NDIKKIVAFSTSSQLGLMMVTIGINQPHLAFLHICTHAFFKAMLFMCSGSIIHNLNNEQDIRKMG 360

  Fly   328 GLSIHMPLTSACFNVSNLALCGMPFLAGFYSKDMILEIVSISNVNMFSFFLYYFSTGLTVSYSFR 392
            ||...|||||....:.:|||.|||||.||||||.|:|..::|..|.::..:...:|.||.:||.|
Human   361 GLLKTMPLTSTSLTIGSLALAGMPFLTGFYSKDHIIETANMSYTNAWALSITLIATSLTSAYSTR 425

  Fly   393 LVYYSMTGDLNCGSLNMLNDESWIMLRGMMGLLIMSIIGGSMLNWLIFP-FPYMICLPIYMKLLT 456
            ::..::||.....:|..:|:.:..:|..:..|...|:..|.::...|.| .|:...:|:|:||..
Human   426 MILLTLTGQPRFPTLTNINENNPTLLNPIKRLAAGSLFAGFLITNNISPASPFQTTIPLYLKLTA 490

  Fly   457 LFVCIVGGLFGYLISLSNLFFLNKSLFMYN-LSTFLGS--MWFMPYISTYGMIFY--PLNYGQLV 516
            |.|..:|     |::..:|.:|...|.|.: |.||..|  :.|.|.| |:..|.|  .|....|.
Human   491 LAVTFLG-----LLTALDLNYLTNKLKMKSPLCTFYFSNMLGFYPSI-THRTIPYLGLLTSQNLP 549

  Fly   517 VKSFDQGWSEYFGGQHLYQ---KLSMYSKTLFLMHNNSLKIYLLLFVFWILILLILL 570
            :...|..|.|....:.:.|   ..|:.:.|    ....:|:|.|.|.|.:::.|:|:
Human   550 LLLLDLTWLEKLLPKTISQHQISTSIITST----QKGMIKLYFLSFFFPLILTLLLI 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ND5	YP_009047273.1	ND5	1..562	CDD:214444	203/567 (36%)
ND5	YP_003024036.1	ND5	16..594	CDD:177170	204/572 (36%)