DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment COX3 and COX3

DIOPT Version :9

Sequence 1:	YP_009047271.1	Gene:	COX3 / 19893540	FlyBaseID:	FBgn0013676	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_006959.1	Gene:	COX3 / 2565701	-ID:		Length:	255	Species:	Caenorhabditis elegans

Alignment Length:	256	Identity:	121/256 - (47%)
Similarity:	164/256 - (64%)	Gaps:	7/256 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 HPFHLVDYSPWPLTGAIGAMTTVSGMVKWFH--QYDISLFVLGNIITILTVYQWWRDVSREGTYQ 69
            |.||::..|.:.......:...:|.:|.:|.  .|::.:|.|.:::.|  .:.|.:|::.|| ..
Worm     3 HNFHILSLSSYAYNLFFASAGMLSSLVMFFKFGLYELFIFTLFSVLFI--SFAWGKDIAMEG-LS 64

  Fly    70 GLHTYAVTIGLRWGMILFILSEVLFFVSFFWAFFHSSLSPAIELGASWPPMGIISFNPFQIPLLN 134
            |.|.:.|..|.::|:|||:.||.:||...||.||.::|.|..|||.:|.|.|:...|||.:||||
Worm    65 GYHNFFVMDGFKFGVILFVFSEFMFFFCIFWTFFDAALVPVHELGETWSPFGMHLVNPFGVPLLN 129

  Fly   135 TAILLASGVTVTWAHHSLMENNHSQTTQGLFFTVLLGIYFTILQAYEYIEAPFTIADSIYGSTFF 199
            |.|||:||||||||||||:.|  ...|..:..|.||..|||.:|..||:||.|:|||.::||.|:
Worm   130 TIILLSSGVTVTWAHHSLLSN--KSCTNSMILTCLLAAYFTGIQLMEYMEASFSIADGVFGSIFY 192

  Fly   200 MATGFHGIHVLIGTTFLLVCLLRHLNNHFSKNHHFGFEAAAWYWHFVDVVWLFLYITIYWW 260
            ::|||||||||.|..||....||.|.|||:.|||.|.|.|..||||||||||||::.:|||
Worm   193 LSTGFHGIHVLCGGLFLAFNFLRLLKNHFNYNHHLGLEFAILYWHFVDVVWLFLFVFVYWW 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
COX3	YP_009047271.1	COX3	4..258	CDD:214439	118/252 (47%)
COX3	NP_006959.1	Heme_Cu_Oxidase_III_like	3..255	CDD:294143	118/253 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	245	1.000	Domainoid score	I1203
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	245	1.000	Inparanoid score	I2046
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62397
OrthoDB	1	1.010	-	-		D1304563at2759
OrthoFinder	1	1.000	-	-		FOG0003223
OrthoInspector	1	1.000	-	-		oto20566
orthoMCL	1	0.900	-	-		OOG6_104028
Panther	1	1.100	-	-	LDO	PTHR11403
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R246
SonicParanoid	1	1.000	-	-		X2639
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.010