DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ATP6 and ATP6

DIOPT Version :9

Sequence 1:	YP_009047270.1	Gene:	ATP6 / 19893539	FlyBaseID:	FBgn0013672	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	YP_003024031.1	Gene:	ATP6 / 4508	HGNCID:	7414	Length:	226	Species:	Homo sapiens

Alignment Length:	227	Identity:	87/227 - (38%)
Similarity:	131/227 - (57%)	Gaps:	14/227 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MMTNLFSVFDPSAIFNFSLNWLSTFLGLLMIPSIYWLMPSRYNIMWNSILLTLHKEFKTLLGPSG 65
            |..|||:.|....|.......|......|:||:..:|:.:|.......::....|:..|:....|
Human     1 MNENLFASFIAPTILGLPAAVLIILFPPLLIPTSKYLINNRLITTQQWLIKLTSKQMMTMHNTKG 65

  Fly    66 HNGSTFIFISLFSLILF---NNFMGLFPYIFTSTSHLTLTLSLALPLWLCFMLYGWINHTQHMFA 127
            ...|    :.|.|||:|   .|.:||.|:.||.|:.|::.|::|:|||...::.|:.:..::..|
Human    66 RTWS----LMLVSLIIFIATTNLLGLLPHSFTPTTQLSMNLAMAIPLWAGTVIMGFRSKIKNALA 126

  Fly   128 HLVPQGTPAILMPFMVCIETISNIIRPGTLAVRLTANMIAGHLLLTLLGNTGPSMSYI-----LV 187
            |.:|||||..|:|.:|.|||||.:|:|..||||||||:.|||||:.|:|:...:||.|     |:
Human   127 HFLPQGTPTPLIPMLVIIETISLLIQPMALAVRLTANITAGHLLMHLIGSATLAMSTINLPSTLI 191

  Fly   188 TFLLMAQIALLVLESAVAMIQSYVFAVLSTLY 219
            .|.::  |.|.:||.|||:||:|||.:|.:||
Human   192 IFTIL--ILLTILEIAVALIQAYVFTLLVSLY 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ATP6	YP_009047270.1	ATP6	1..224	CDD:214441	87/227 (38%)
ATP6	YP_003024031.1	ATP6	1..226	CDD:177163	87/227 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143766
Domainoid	1	1.000	135	1.000	Domainoid score	I4999
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	139	1.000	Inparanoid score	I4522
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55185
OrthoDB	1	1.010	-	-		D1095315at2759
OrthoFinder	1	1.000	-	-		FOG0002431
OrthoInspector	1	1.000	-	-		oto90018
orthoMCL	1	0.900	-	-		OOG6_102362
Panther	1	1.100	-	-	LDO	PTHR11410
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R115
SonicParanoid	1	1.000	-	-		X4129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	13	12.940