DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment COX1 and cox1

DIOPT Version :9

Sequence 1:	YP_009047267.1	Gene:	COX1 / 19893533	FlyBaseID:	FBgn0013674	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	YP_009472108.1	Gene:	cox1 / 36335686	-ID:	-	Length:	527	Species:	Arabidopsis thaliana

Alignment Length:	515	Identity:	354/515 - (68%)
Similarity:	425/515 - (82%)	Gaps:	9/515 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 QWLFSTNHKDIGTLYFIFGAWAGMVGTSLSILIRAELGHPGALI--GDDQIYNVIVTAHAFIMIF 65
            :|||||||||||||||||||.||::||..|:|||.||..||..|  |:.|:|||::|||||:|||
plant     6 RWLFSTNHKDIGTLYFIFGAIAGVMGTCFSVLIRMELARPGDQILGGNHQLYNVLITAHAFLMIF 70

  Fly    66 FMVMPIMIGGFGNWLVPLMLGAPDMAFPRMNNMSFWLLPPALSLLLVSSMVENGAGTGWTVYPPL 130
            |||||.||||||||.||:::|||||||||:||:|||||||:|.|||.|::||.|:||||||||||
plant    71 FMVMPAMIGGFGNWFVPILIGAPDMAFPRLNNISFWLLPPSLLLLLSSALVEVGSGTGWTVYPPL 135

  Fly   131 SAGIAHGGASVDLAIFSLHLAGISSILGAVNFITTVINMRSTGISLDRMPLFVWSVVITALLLLL 195
            |...:|.|.:||||||||||:|:|||||::|||||:.|||..|:::.|:|||||||::||.||||
plant   136 SGITSHSGGAVDLAIFSLHLSGVSSILGSINFITTIFNMRGPGMTMHRLPLFVWSVLVTAFLLLL 200

  Fly   196 SLPVLAGAITMLLTDRNLNTSFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIISQES 260
            |||||||||||||||||.||:||||||||||||||||||||||||||||||||||:||||:|..|
plant   201 SLPVLAGAITMLLTDRNFNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGIISHIVSTFS 265

  Fly   261 GKKETFGSLGMIYAMLAIGLLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAVPTGIKIFSWLATL 325
            | |..||.|||:|||::||:|||:||||||||||:|||||||||:||||||||||||||||:||:
plant   266 G-KPVFGYLGMVYAMISIGVLGFLVWAHHMFTVGLDVDTRAYFTAATMIIAVPTGIKIFSWIATM 329

  Fly   326 HGTQLSYSPAILWALGFVFLFTVGGLTGVVLANSSVDIILHDTYYVVAHFHYVLSMGAVFAIMAG 390
            .|..:.|...:|:|:||:||||:|||||:|||||.:||.||||||||||||||||||||||:.||
plant   330 WGGSIQYKTPMLFAVGFIFLFTIGGLTGIVLANSGLDIALHDTYYVVAHFHYVLSMGAVFALFAG 394

  Fly   391 FIHWYPLFTGLTLNNKWLKSHFIIMFIGVNLTFFPQHFLGLAGMPRRYSDYPDAYTTWNIVSTIG 455
            |.:|.....|.|......:.||.|.|.||||||||.|||||:|||||..||||||..||.:|:.|
plant   395 FYYWVGKIFGRTYPETLGQIHFWITFFGVNLTFFPMHFLGLSGMPRRIPDYPDAYAGWNALSSFG 459

  Fly   456 STISLLGILFFFFIIWESLVS---QRQVIYP--IQLNS-SIEWYQNTPPAEHSYSELPLL 509
            |.||::||..||.::..:|.|   :|....|  ::||| ::||...:|||.|::.|||.:
plant   460 SYISVVGICCFFVVVTITLSSGNNKRCAPSPWALELNSTTLEWMVQSPPAFHTFGELPAI 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
COX1	YP_009047267.1	COX1	1..511	CDD:177210	354/515 (69%)
cox1	YP_009472108.1	Cyt_c_Oxidase_I	11..504	CDD:238833	343/493 (70%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	679	1.000	Domainoid score	I19
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	729	1.000	Inparanoid score	I115
OMA	1	1.010	-	-		QHG61018
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002409
OrthoInspector	1	1.000	-	-		oto3549
orthoMCL	1	0.900	-	-		OOG6_102770
Panther	1	1.100	-	-	LDO	PTHR10422
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1600
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.970