Protein Alignment Rpe65 and ninaB

DIOPT Version :9

• Sequence 1: XP_006501228.1
• Gene: Rpe65 / 19892
• MGIID: 98001
• Length: 534
• Species: Mus musculus
• Sequence 2: NP_650307.2
• Gene: ninaB / 41678
• FlyBaseID: FBgn0002937
• Length: 620
• Species: Drosophila melanogaster
• Alignment Length: 576
• Identity: 197/576 - (34%)
• Similarity: 286/576 - (49%)
• Gaps: 77/576 - (13%)

Mouse    21 ELSSPLTAHVTGRIPLWLTGSLLRCGPGLFEVGSEPFYHLFDGQALLHKFDFKEGHVTYHRRFIR 85
            |:..|:..|.:|.||.|:.|||||.|||.::||...|.||||..||||:|..:.|.|||..||:.
  Fly    52 EIVDPIEGHHSGHIPKWICGSLLRNGPGSWKVGDMTFGHLFDCSALLHRFAIRNGRVTYQNRFVD 116

Mouse    86 TDAYVRAMTEKRIVITEFGTCAFPDPCKNIFSRFFSYFKGVEVTDNALVNIYPVGEDYYACTETN 150
            |:...:..:.:|||:|||||.|.||||.:||.||.:.|:....|||::::|||.|:.||..|||.
  Fly   117 TETLRKNRSAQRIVVTEFGTAAVPDPCHSIFDRFAAIFRPDSGTDNSMISIYPFGDQYYTFTETP 181

Mouse   151 FITKINPETLETIKQVDLCNYISVNGATAHPHIESDGTVYNIGNCFGKNFTVAYNIIKIPPLKAD 215
            |:.:|||.||.|..::...:::.|...|:|||:...|||||:|....:: ..||.|:..|    .
  Fly   182 FMHRINPCTLATEARICTTDFVGVVNHTSHPHVLPSGTVYNLGTTMTRS-GPAYTILSFP----H 241

Mouse   216 KEDPINKSEVVVQFPCSDRFKPSYVHSFGLTPNYIVFVETPVKINLFKFLSSWSLWGANYMDCFE 280
            .|.....:.||...||..:..|.|:|:||||.:|.|.||.|:.::|.:::.: .|.|.|...|.:
  Fly   242 GEQMFEDAHVVATLPCRWKLHPGYMHTFGLTDHYFVIVEQPLSVSLTEYIKA-QLGGQNLSACLK 305

Mouse   281 SNESMGVWLHVADKKRRKYFNNKYRTSPFNLFHHINTYEDNGFLIVDLCCWKGFEFVYNYLYL-- 343
            ..|......|:.|:...|.... |.:..|...|.||.:|.:|.::||:|.::..|.: |.:||
  Fly   306 WFEDRPTLFHLIDRVSGKLVQT-YESEAFFYLHIINCFERDGHVVVDICSYRNPEMI-NCMYLEA 368

Mouse   344 -ANLREN-----------------------WEEVKRNAMK--------APQ------PEVRRYV- 369
             ||::.|                       ....||..:|        |||      ..|.:|.
  Fly   369 IANMQTNPNYATLFRGRPLRFVLPLGTIPPASIAKRGLVKSFSLAGLSAPQVSRTMKHSVSQYAD 433

Mouse   370 ---LPLTIDKVDTGR------------------NLVTLPHTTATATLRSDETIWLEPEVLFSGPR 413
               :|....:...|.                  ||||:..:.|.| .:....|.|.||:|..
  Fly   434 ITYMPTNGKQATAGEESPKRDAKRGRYEEENLVNLVTMEGSQAEA-FQGTNGIQLRPEMLCD--- 494

Mouse   414 QAFEFPQINYQKFGGKPYTYAYGLGLN-HFVPDKQLCKMNVKTKEIWMWQEPDSYPSEPIFVSQP 477
            ...|.|:|.|:::.||.|.|.|.:..: ..|....|.|::|..|....|.|.:.||||||||..|
  Fly   495 WGCETPRIYYERYMGKNYRYFYAISSDVDAVNPGTLIKVDVWNKSCLTWCEENVYPSEPIFVPSP 559

Mouse   478 DALEEDDGVVLSVVVSPGAGQKPAYLLVLNAKDLSEIARAEVETN--IPVTFHGLF 531
            |...|||||:|:.:|..|...:...|:||.||.::|:.|.:..||  :|...||.|
  Fly   560 DPKSEDDGVILASMVLGGLNDRYVGLIVLCAKTMTELGRCDFHTNGPVPKCLHGWF 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpe65	XP_006501228.1	RPE65	21..531	CDD:376981	196/574 (34%)
ninaB	NP_650307.2	RPE65	52..617	CDD:281102	197/576 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837711
Domainoid	1	1.000	278	1.000	Domainoid score	I1693
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	278	1.000	Inparanoid score	I2906
Isobase	1	0.950	-	0.917438	Normalized mean entropy	S5013
OMA	1	1.010	-	-		QHG59724
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000856
OrthoInspector	1	1.000	-	-		otm42882
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10543
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5415
SonicParanoid	1	1.000	-	-		X319
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.980