Protein Alignment Slc22a8 and CarT

DIOPT Version :9

• Sequence 1: NP_001158106.1
• Gene: Slc22a8 / 19879
• MGIID: 1336187
• Length: 537
• Species: Mus musculus
• Sequence 2: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Alignment Length: 582
• Identity: 166/582 - (28%)
• Similarity: 264/582 - (45%)
• Gaps: 98/582 - (16%)

Mouse     5 EILDRVGSMGPFQYLHVTLLALPI---LGIANHNLLQIFTATTPDHH-CRPPPNASLEPWVLPLG 65
            ::|..:|..|.:|.|.|..:.||.   .|....|  |:|.|.|||.: ||.|     |...|||.
  Fly    38 DLLPTIGEFGKYQKLLVFGICLPACIPCGFCAFN--QLFMADTPDDYWCRIP-----ELLDLPLE 95

Mouse    66 PNGK---PE----------KC----LRFVHL-------------PNASLPNDTQGATEPCLDGWI 100
            ....   |:          ||    :.:..|             ||||.|      ...|..||.
  Fly    96 QRKSLSIPKELDNDELVYSKCYTYGVNWTQLLESGEEDDLTTMEPNASWP------LIKCPQGWE 154

Mouse   101 YNST--RDTIVTEWDLVCGSNKLKEMAQSVFMAGILVGGPV----FGELSDRFGRKPILTWSYLL 159
            ||::  ..:||.::||||.    :::..::.:|.:..||||    ||.|:||.||:    .||.:
  Fly   155 YNTSVVWSSIVIDFDLVCD----QDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRR----LSYFV 211

Mouse   160 ----LAASGSSAAFSPSLTVYMIFRFLCGCSISGISLSTIILNVEWVPTSTRAISSTTIGYC--Y 218
                |.|.....:.|.....:...|.:.|.:|..:.....|:::|.|..:.|  |..|:..|  |
  Fly   212 CLATLLAGSLMTSLSKDFWTWAGSRVIVGLTIPAVYQIPFIISLELVGENYR--SFVTVMTCTFY 274

Mouse   219 TIGQFILPGLAYAVPQWRWLQLSVSAAFFIFSLLSWWVPESIRWLVLSGKFSKALKTLQRVATFN 283
            |.|..:|.|:.|....|..|....|..|:.:.|..:.:|||.|||::.|:..:|||.|:|:|..|
  Fly   275 TSGIMLLSGVTYLERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVN 339

Mouse   284 GKKEEGEKLTVEELKFNLQKDITSAKVK--------YGLSDLFRVSILRRVTFCLSLAWFAT--- 337
            |::      ..|.:...|:..|...|:|        .||:||.|...:|..|..::|:|||.
  Fly   340 GRE------FPEAVHLKLEAQIRRDKLKKQKKKMANVGLADLCRTPNMRLKTILITLSWFANETV 398

Mouse   338 --GFAYYSLAMGVEEFGVNIYILQIIFGGVDIPAKFITILSISYLGRRITQGFLLILAGVAILAL 400
              |.:||..|:|..:: |:.::..:    |::|:.......:...|||......:||.|||.:..
  Fly   399 YLGLSYYGPALGTNQY-VSFFLSAV----VELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVIT 458

Mouse   401 IFVSSEMQLLRTALAVFGKGCLSGSFSCLFLYTSELYPTVLRQTGMGISNIWARVGSMIAPLVKI 465
            :.:..:.......|.:..|..||.||..::.:..|||||.:|..|:|.|:....:|.:..|.:..
  Fly   459 VMLPDDAVDETLVLYLVSKALLSASFLIIYPFAGELYPTQVRGIGIGASSYIGGLGLIGIPFITY 523

Mouse   466 TGELQPFIPNVIFGTMTLLGGSAAFFLLETLNRPLPETIEDIQD----W-YQQTKKTKQEPE 522
            .|:....:|.||.|.:::|||.....|.|||:..||:|||:.::    | ::...:..|:||
  Fly   524 LGKDNLKLPLVIMGFLSMLGGMTGLRLPETLHHRLPQTIEEGEEFGKNWQFKDCCRCAQKPE 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slc22a8	NP_001158106.1	2A0119	11..503	CDD:273328	158/550 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	513..537		3/10 (30%)
CarT	NP_610052.1	2A0119	44..561	CDD:273328	158/550 (29%)
		MFS	182..551	CDD:119392	110/385 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	74	1.000	Domainoid score	I9078
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.020