Protein Alignment Cyp6a16 and DIT2

DIOPT Version :10

• Sequence 1: NP_001285631.1
• Gene: Cyp6a16 / 19836250
• FlyBaseID: FBgn0031726
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_010690.1
• Gene: DIT2 / 852011
• SGDID: S000002810
• Length: 489
• Species: Saccharomyces cerevisiae
• Alignment Length: 501
• Identity: 115/501 - (22%)
• Similarity: 215/501 - (42%)
• Gaps: 79/501 - (15%)

  Fly     5 LLLLTSLLSFL-LGYLRYRFTYWEL---RGIPQLRPHFLF-GHFFRL-QSVHYSELLQETYDAFR 63
            ||.|..|:.|| |.|:.:......|   :.||.:..:.:| ...|.: |:..|...::|:.:.:
Yeast     3 LLKLLCLILFLTLSYVAFAIIVPPLNFPKNIPTIPFYVVFLPVIFPIDQTELYDLYIRESMEKY- 66

  Fly    64 GSAKVAGTYVFLRPMAVVLDLDLVKAVLIRDFNNFVDRRSFHGDPLTA-------NLFNLQGEEW 121
            |:.|    :.|.....:::......|.:.:|.:.|....:....|.:|       |:.:..|..|
Yeast    67 GAVK----FFFGSRWNILVSRSEYLAQIFKDEDTFAKSGNQKKIPYSALAAYTGDNVISAYGAVW 127

  Fly   122 RNLRTKL---------SPTFTSGKMKYMFGTVSTVAQQLGGTFDELVGSQGAVLELHDLMARYTT 177
            ||.|..:         :|.|.:.|:      :.|:.:      :.|:..|.:: .:..|..|...
Yeast   128 RNYRNAVTNGLQHFDDAPIFKNAKI------LCTLIK------NRLLEGQTSI-PMGPLSQRMAL 179

  Fly   178 DVIGSCAFGTECSSLREPQAEFRQVGRRIFRNSNRSIRWRIFKMTYLSSLAKLGLPVRILHPDIT 242
            |.|...|.|.:..:|...:..|.:   .:.|     |:.:||...:|:......||:    |...
Yeast   180 DNISQVALGFDFGALTHEKNAFHE---HLIR-----IKKQIFHPFFLTFPFLDVLPI----PSRK 232

  Fly   243 KFFNRIV--RETVELRERENIRRNDFMD----LLLDLRRQENGKGLTMEQMAAQAFVFFVAGFET 301
            |.|..:|  ||.:..|.::.:..|...:    ...||.|..|.:.:..:|:.....:..|||.|.
Yeast   233 KAFKDVVSFRELLVKRVQDELVNNYKFEQTTFAASDLIRAHNNEIIDYKQLTDNIVIILVAGHEN 297

  Fly   302 SSSNMSYALFELAK-NQDVQQKLRMEINDSIGKHGKLTYEAMMEMPYLDQTITETLRKYPALSS- 364
            .....:.:|:.||| :.:.|:|||.|:|      |....:.:.::|.|:..:.|.:|.||.||:
Yeast   298 PQLLFNSSLYLLAKYSNEWQEKLRKEVN------GITDPKGLADLPLLNAFLFEVVRMYPPLSTI 356

  Fly   365 LTRLASEDYEIPSPDGGDPVVLEKGTSVHIPVLAIHYDPEVY-PEPHEFRPERFAPD--ACRE-- 424
            :.|..::..::     |..:|:.||..|........:||:.: ....:|:|||:..|  ..|:
Yeast   357 INRCTTKTCKL-----GAEIVIPKGVYVGYNNFGTSHDPKTWGTTADDFKPERWGSDIETIRKNW 416

  Fly   425 ---RHPTAFLGFGDGPRNCIGLRFGRMQVKVGLITLLRRFRFSLPP 467
               ::..|..||..|.|.|:|.:....::::.|..:|::||:||.|
Yeast   417 RMAKNRCAVTGFHGGRRACLGEKLALTEMRISLAEMLKQFRWSLDP 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a16	NP_001285631.1	CYP6-like	64..489	CDD:410679	99/436 (23%)
DIT2	NP_010690.1	CYP56-like	65..485	CDD:410693	99/439 (23%)