DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp6a16 and CYP714A2

DIOPT Version :9

Sequence 1:	NP_001285631.1	Gene:	Cyp6a16 / 19836250	FlyBaseID:	FBgn0031726	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	NP_197872.1	Gene:	CYP714A2 / 832559	AraportID:	AT5G24900	Length:	525	Species:	Arabidopsis thaliana

Alignment Length:	531	Identity:	135/531 - (25%)
Similarity:	234/531 - (44%)	Gaps:	79/531 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 FLLGYLRYR---FTYWELR------GIPQLRPHFLFGHFFRLQSVH---------------YSEL 54
            |.:||..|.   ...|.:|      |:....|....|:...:|.:.               ||..
plant    21 FSVGYHVYGRAVVEQWRMRRSLKLQGVKGPPPSIFNGNVSEMQRIQSEAKHCSGDNIISHDYSSS 85

  Fly    55 LQETYDAFRGSAKVAGTY-------VFLRPMAVVLDLDLVKAVLIRDFNNFVDRRSFHGDPLTAN 112
            |...:|.:|.......||       :::....:|.:|.....:.:....:...|.    :|:..|
plant    86 LFPHFDHWRKQYGRIYTYSTGLKQHLYINHPEMVKELSQTNTLNLGRITHITKRL----NPILGN 146

  Fly   113 -LFNLQGEEWRNLRTKLSPTFTSGKMKYMFGTVSTVAQQLGGTFDELV---GSQGAVLELHDLMA 173
             :....|..|.:.|..::..||..|:|.|.|.:...|..:...::|:|   |..|..:.:.:.:.
plant   147 GIITSNGPHWAHQRRIIAYEFTHDKIKGMVGLMVESAMPMLNKWEEMVKRGGEMGCDIRVDEDLK 211

  Fly   174 RYTTDVIGSCAFGTECSSLREPQAEFRQVGRRIFRNSNRSIRWRIFKMTYLSSLAKLGLPVRILH 238
            ..:.|||....||   ||..:.:|.|..:...:...:.||:.:|....|.:...:|       .|
plant   212 DVSADVIAKACFG---SSFSKGKAIFSMIRDLLTAITKRSVLFRFNGFTDMVFGSK-------KH 266

  Fly   239 PDI-----TKFFNRIVRETVELRERE--NIRRNDFMDLLLDLRRQENGKGLTMEQMAAQAFV--- 293
            .|:     .......:.|||:.||.|  :..:.|.|.|:|: ....:..|...::.|.:.||
plant   267 GDVDIDALEMELESSIWETVKEREIECKDTHKKDLMQLILE-GAMRSCDGNLWDKSAYRRFVVDN 330

  Fly   294 ---FFVAGFETSSSNMSYALFELAKNQDVQQKLRMEINDSIGKHGKLTYEAMMEMPYLDQTITET 355
               .:.||.::::.::|:.|..||.|...|.|:|.||..|. |:|....|::..:..:...|.||
plant   331 CKSIYFAGHDSTAVSVSWCLMLLALNPSWQVKIRDEILSSC-KNGIPDAESIPNLKTVTMVIQET 394

  Fly   356 LRKYPALSSLTRLASEDYEIPSPDGGDPVVLEKGTSVHIPVLAIHYDPEVY-PEPHEFRPERFA- 418
            :|.||....:.|.||:|..:     || :|:.||..:...:.|:|.|||:: |:.::|:||||:
plant   395 MRLYPPAPIVGREASKDIRL-----GD-LVVPKGVCIWTLIPALHRDPEIWGPDANDFKPERFSE 453

  Fly   419 --PDACRERHPTAFLGFGDGPRNCIGLRFGRMQVKVGLITLLRRFRFSLPPGSPTQLKVTKRNLI 481
              ..||  ::|.:::.||.|||.|:|..||.|:|||.:..::.:|.|:|   |||........|:
plant   454 GISKAC--KYPQSYIPFGLGPRTCVGKNFGMMEVKVLVSLIVSKFSFTL---SPTYQHSPSHKLL 513

  Fly   482 LLPSDGVRLQV 492
            :.|..||.::|
plant   514 VEPQHGVVIRV 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a16	NP_001285631.1	p450	32..492	CDD:278495	127/502 (25%)
CYP714A2	NP_197872.1	p450	37..524	CDD:299894	129/513 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910